He Jian, Xu Jie, Zhou Hong-Yan
aDepartment of Pathology, Tongji Hospital, Tongji University School of Medicine, Shanghai bSchool of Public Health, Xinxiang Medical University cDepartment of Pathology, The First People's Hospital of Xinxiang, Xinxiang, P. R. China.
Medicine (Baltimore). 2016 Sep;95(39):e4961. doi: 10.1097/MD.0000000000004961.
Uterus-like mass (ULM) is an extremely rare lesion. Gross morphology of ULM resembling a uterus. It can occur in various organs in the abdominal cavity, even in the spinal cord. The histogenesis of ULM remains uncertain. A number of hypotheses have been proposed including metaplasia, congenital anomaly, and heterotopia theory.
We describe a case of 43-year-old male presented with a complaint of acute low abdominal pain. Pelvic ultrasound found a large pelvic mass embedded in the broad ligament.
The mass contains a variable thickness smooth muscle layer lined with endometrial glands and stroma which resembling a uterus. Eventually, the patient was diagnosed as ULM by histopathological examination.
Except hypomenorrhea, the patient did not have any other associated abnormalities. We suggest this case supports the metaplasia theory that ULM is a benign mass formed by the proliferation of ectopic endometrial stromal cells or pluripotent mesenchymal cells of the 2nd Müllerian system.
子宫样肿块(ULM)是一种极其罕见的病变。ULM的大体形态类似于子宫。它可发生于腹腔的各种器官,甚至脊髓。ULM的组织发生仍不确定。已经提出了许多假说,包括化生、先天性异常和异位理论。
我们描述了一例43岁男性,主诉急性下腹痛。盆腔超声发现一个大的盆腔肿块包埋于阔韧带内。
肿块包含一层厚度不一的平滑肌层,内衬子宫内膜腺体和间质,类似子宫。最终,患者经组织病理学检查诊断为ULM。
除月经量少外,患者无任何其他相关异常。我们认为该病例支持化生理论,即ULM是由异位子宫内膜间质细胞或第二苗勒系统的多能间充质细胞增殖形成的良性肿块。