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孤立性原发性额骨骨瘤的罕见临床病例。

A rare clinical case of the isolated primary frontal bone osteoma.

作者信息

Pohranychna Kh

机构信息

Department of Oral and Maxillofacial Surgery, Danylo Halytsky Lviv National Medical University, Lviv 79010, Ukraine.

出版信息

Exp Oncol. 2016 Sep;38(3):204-6.

Abstract

AIM

To study a rare clinical case of isolated primary osteoma localized in the frontal bone, provide its detailed clinical and pathomorphological analysis, and evaluate statistical indicators of occurrence frequency and localization of facial skeleton osteomas during 2006-2015.

MATERIALS AND METHODS

The retrospective case records analysis of patients undergoing treatment in the ma-xillofacial department of Lviv Regional Clinical Hospital and suffering from facial skeleton osteomas was conducted. The clinical examination was carried out in accordance with the inspection protocol required for the examination of patients diagnosed with tumors and tumor-like neoplasms in a particular clinical case. Frontal and lateral views were used in the course of X-ray imaging. Histological studies included macroscopy and microscopy.

RESULTS

According to the retrospective case record analysis made over the last 10 years 346 cases of facial bone osteoma were revealed and proved histologically comprising 3.7% of all benign osteogeneous maxillofacial tumors. For the first time in 10 years osteoma localized in the frontal bone had been revealed and thoroughly studied. Macroscopically - a semi-spherical and immovable neoformation 7 cm in diameter of hard consistency, splaying out at 4 cm and being adherent with the frontal bone. Roentgenologically - homogeneous intense shadowing of a round form with relatively distinct outlines complying with clinical sizes. According to the histological data, the tumor consists mostly of the solid osseous tissue and the spongy osseous tissue with the evident thickened trabeculas of the bone located in different directions.

CONCLUSION

The analysis of historical data demonstrated extremely rare localization of primary osteoma of the frontal bone, and indicated the uniqueness of the case and significant clinical importance of its detailed study.

摘要

目的

研究一例罕见的孤立性原发性骨瘤位于额骨的临床病例,提供详细的临床和病理形态学分析,并评估2006 - 2015年面部骨骼骨瘤发生频率和定位的统计指标。

材料与方法

对利沃夫地区临床医院颌面外科接受治疗的面部骨骼骨瘤患者的病例记录进行回顾性分析。临床检查按照特定临床病例中诊断为肿瘤和肿瘤样新生物的患者检查所需的检查方案进行。X线成像过程中采用正位和侧位视图。组织学研究包括大体检查和显微镜检查。

结果

根据过去10年的回顾性病例记录分析,共发现346例面部骨骨瘤并经组织学证实,占所有良性骨源性颌面肿瘤的3.7%。10年来首次发现并深入研究了位于额骨的骨瘤。大体上,为一个直径7厘米、质地坚硬、呈半球形且不可移动的新生物,在4厘米处展开并与额骨粘连。X线表现为圆形、均匀致密阴影,轮廓相对清晰,与临床大小相符。根据组织学数据,肿瘤主要由实性骨组织和海绵状骨组织组成,骨小梁明显增厚且分布于不同方向。

结论

历史数据分析表明额骨原发性骨瘤的定位极其罕见,表明该病例的独特性及其详细研究的重要临床意义。

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