蓝藻噬菌体基因组中的代谢基因：对多样性和进化的影响。
Metabolic Genes within Cyanophage Genomes: Implications for Diversity and Evolution.
作者信息
Gao E-Bin, Huang Youhua, Ning Degang
机构信息
School of The Environment and Safety Engineering, Jiangsu University, No. 301, Xuefu Road, Zhenjiang 212013, Jiangsu Province, China.
Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, No. 164, Xingangxi Road, Haizhu District, Guangzhou 5103401, Guangdong Province, China.
出版信息
Genes (Basel). 2016 Sep 29;7(10):80. doi: 10.3390/genes7100080.
Cyanophages, a group of viruses specifically infecting cyanobacteria, are genetically diverse and extensively abundant in water environments. As a result of selective pressure, cyanophages often acquire a range of metabolic genes from host genomes. The host-derived genes make a significant contribution to the ecological success of cyanophages. In this review, we summarize the host-derived metabolic genes, as well as their origin and roles in cyanophage evolution and important host metabolic pathways, such as the light-dependent reactions of photosynthesis, the pentose phosphate pathway, nutrient acquisition and nucleotide biosynthesis. We also discuss the suitability of the host-derived metabolic genes as potential diagnostic markers for the detection of genetic diversity of cyanophages in natural environments.
噬蓝藻体是一类专门感染蓝细菌的病毒，具有遗传多样性，在水环境中广泛存在。由于选择压力，噬蓝藻体常常从宿主基因组中获得一系列代谢基因。这些源自宿主的基因对噬蓝藻体在生态上的成功起到了重要作用。在这篇综述中，我们总结了源自宿主的代谢基因，以及它们在噬蓝藻体进化中的起源和作用，还有重要的宿主代谢途径，如光合作用的光反应、磷酸戊糖途径、营养物质获取和核苷酸生物合成。我们还讨论了源自宿主的代谢基因作为检测自然环境中噬蓝藻体遗传多样性的潜在诊断标志物的适用性。
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