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三柱与五柱电极脊髓刺激治疗腰椎手术失败综合征的临床疗效及电极位置的计算机断层扫描分析比较

Comparison of Clinical Efficacy and Computed Tomographic Analysis of Lead Position Between Three-Column and Five-Column Paddle Leads Spinal Cord Stimulation for Failed Back Surgery Syndrome.

作者信息

Choi Jin-Gyu, Ha Sang-Woo, Son Byung-Chul

机构信息

Department of Neurosurgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Department of Neurosurgery, Chosun University Hospital, Chosun University, Gwangju, Republic of Korea.

出版信息

World Neurosurg. 2017 Jan;97:292-303. doi: 10.1016/j.wneu.2016.10.012. Epub 2016 Oct 12.

Abstract

OBJECTIVE

To investigate the difference in clinical outcome and the position of paddle lead spinal cord stimulation (SCS) between 3-column and 5-column paddle lead SCS in patients with failed back surgery syndrome.

METHODS

In 21 patients who underwent paddle lead SCS at T9 (3-column, n = 9; 5-column, n =12) for failed back surgery syndrome, a 12-month follow-up numerical rating scale, percent pain relief, and computed tomography assessment of contact angle and percent reduction of T9 canal area were investigated.

RESULTS

There was no difference in paresthesia coverage of the painful area, trial success rate, clinical outcomes, and percent pain relief between the 2 groups (P >0.05). The contact angle in the 5-column group was generally more than that of the 3-column group (P = 0.067). Overall reduction of 35.51% ± 4.76% in the T9 canal was observed and there was no difference between the 2 groups (P >0.05) and no correlation between the contact angle and percent T9 spinal canal reduction (r = -0.247, P > 0.05).

CONCLUSIONS

Although clinical efficacy of SCS using three-column and five-column paddle lead was not significant different from each other, significant inclination of paddle lead in posterior epidural space with significant reduction in T9 canal area were observed in both groups. The degree of inclination in the 5-column group was more than that in the 3-column lead group. Close approximation of paddle lead contacts to dorsal spinal cord with reduced dorsal cerebrospinal fluid space and intraoperative neurophysiologic guidance might have contributed to the high rate of trial success and long-term pain control.

摘要

目的

探讨在腰椎手术失败综合征患者中,三柱式与五柱式极板脊髓刺激(SCS)的临床结局差异及极板位置情况。

方法

对21例因腰椎手术失败综合征在T9节段接受极板脊髓刺激术的患者(三柱式,n = 9;五柱式,n = 12)进行研究,随访12个月,调查数字评分量表、疼痛缓解百分比,以及通过计算机断层扫描评估接触角和T9椎管面积减少百分比。

结果

两组之间在疼痛区域的感觉异常覆盖范围、试验成功率、临床结局和疼痛缓解百分比方面均无差异(P > 0.05)。五柱式组的接触角总体上大于三柱式组(P = 0.067)。观察到T9椎管总体减少35.51% ± 4.76%,两组之间无差异(P > 0.05),且接触角与T9椎管减少百分比之间无相关性(r = -0.247,P > 0.05)。

结论

虽然使用三柱式和五柱式极板的脊髓刺激术临床疗效无显著差异,但两组均观察到极板在硬膜外后间隙有明显倾斜,且T9椎管面积显著减小。五柱式组的倾斜程度大于三柱式组。极板接触点与脊髓背侧紧密贴近,背侧脑脊液间隙减小,以及术中神经生理引导可能有助于提高试验成功率和长期疼痛控制。

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