Okada Y, Suzuki H, Ishiyama I
Aust Dent J. 1989 Aug;34(4):323-5. doi: 10.1111/j.1834-7819.1989.tb04640.x.
A case is described of sudden death occurring after the use of a noradrenaline-containing local anaesthetic. Autopsy revealed a massive subarachnoid haemorrhage following a ruptured cerebral aneurysm. The noradrenaline in the local anaesthetic is thought to be an important factor in the cause of the rupture. It is recommended that preparations containing 1:25,000 noradrenaline not be used.
本文描述了一例在使用含去甲肾上腺素的局部麻醉剂后发生猝死的病例。尸检发现脑动脉瘤破裂后出现大量蛛网膜下腔出血。局部麻醉剂中的去甲肾上腺素被认为是导致破裂的一个重要因素。建议不要使用含1:25,000去甲肾上腺素的制剂。