Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan 430022, P. R. China.
Sci Rep. 2016 Oct 18;6:34795. doi: 10.1038/srep34795.
This study sought to compare the image quality and radiation dose of coronary computed tomography angiography (CCTA) from prospectively triggered 128-slice CT (128-MSCT) versus dual-source 64-slice CT (DSCT). The study was approved by the Medical Ethics Committee at Tongji Medical College of Huazhong University of Science and Technology. Eighty consecutive patients with stable heart rates lower than 70 bpm were enrolled. Forty patients were scanned with 128-MSCT, and the other 40 patients were scanned with DSCT. Two radiologists independently assessed the image quality in segments (diameter >1 mm) according to a three-point scale (1: excellent; 2: moderate; 3: insufficient). The CCTA radiation dose was calculated. Eighty patients with 526 segments in the 128-MSCT group and 544 segments in the DSCT group were evaluated. The image quality 1, 2 and 3 scores were 91.6%, 6.9% and 1.5%, respectively, for the 128-MSCT group and 97.6%, 1.7% and 0.7%, respectively, for the DSCT group, and there was a statistically significant inter-group difference (P ≤ 0.001). The effective doses were 3.0 mSv in the 128-MSCT group and 4.5 mSv in the DSCT group (P ≤ 0.001). Compared with DSCT, CCTA with prospectively triggered 128-MSCT had adequate image quality and a 33.3% lower radiation dose.
本研究旨在比较前瞻性触发 128 层 CT（128-MSCT）与双源 64 层 CT（DSCT）冠状动脉 CT 血管造影（CCTA）的图像质量和辐射剂量。该研究得到华中科技大学同济医学院医学伦理委员会的批准。连续纳入 80 例心率低于 70bpm 的稳定型患者。40 例患者行 128-MSCT 扫描，另 40 例患者行 DSCT 扫描。两名放射科医生独立根据三分制（1：优；2：良；3：差）对直径>1mm 的节段进行图像质量评估。计算 CCTA 辐射剂量。128-MSCT 组 80 例患者共 526 个节段，DSCT 组 80 例患者共 544 个节段。128-MSCT 组的图像质量评分 1、2 和 3 分别为 91.6%、6.9%和 1.5%，DSCT 组分别为 97.6%、1.7%和 0.7%，两组间差异有统计学意义（P≤0.001）。128-MSCT 组的有效剂量为 3.0mSv，DSCT 组为 4.5mSv（P≤0.001）。与 DSCT 相比，前瞻性触发 128-MSCT 的 CCTA 具有足够的图像质量，辐射剂量降低了 33.3%。
