Dreizen S, Stern M H, Levy B M
J Dent Res. 1978 Feb;57(2):412-7. doi: 10.1177/00220345780570024501.
Advanced atherosclerosis in the form of fibro-fatty intimal plaques has been produced in the rabbit aorta and oral vasculature (labial, lingual, gingival, palatal, periodontal and alveolar arteries) by dietary means. The animals were fed a hypercholesteremic diet and a normocholesteremic diet on alternate months for two years. In the aorta and in many of the oral vessels, the formation of the intimal atheromas was paralleled by a degeneration of the tunica media. The lingual arteries rivaled the aorta and coronary arteries in vulnerability to the diet-induced arteriopathies.
通过饮食方式，在兔主动脉和口腔血管（唇动脉、舌动脉、牙龈动脉、腭动脉、牙周动脉和牙槽动脉）中形成了纤维脂肪内膜斑块形式的晚期动脉粥样硬化。这些动物交替喂食高胆固醇饮食和正常胆固醇饮食，持续两年。在主动脉和许多口腔血管中，内膜动脉粥样瘤的形成与中膜退变同时发生。舌动脉在对饮食诱导的动脉病变的易感性方面可与主动脉和冠状动脉相媲美。
