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多瑙河地区的围产期健康——新出生队列研究的合理性

Perinatal health in the Danube region - new birth cohort justified.

作者信息

Knudsen Lisbeth E, Andersen Zorana J, Sram Radim J, Braun Kohlová Markéta, Gurzau Eugen S, Fucic Aleksandra, Gribaldo Laura, Rossner Pavel, Rossnerova Andrea, Máca Vojtěch, Zvěřinová Iva, Gajdosova Dagmar, Moshammer Hanns, Rudnai Peter, Ščasný Milan

出版信息

Rev Environ Health. 2017 Mar 1;32(1-2):9-14. doi: 10.1515/reveh-2016-0038.

DOI:10.1515/reveh-2016-0038
PMID:27754971
Abstract

In 2013-2015, a consortium of European scientists - NEWDANUBE - was established to prepare a birth cohort in the Danube region, including most of the countries with the highest air pollution in Europe, the area being one-fifth of the European Union's (EU's) territory, including 14 countries (nine EU member states), over 100 million inhabitants, with numerous challenges: big socioeconomic disparities, and a region-specific environmental pollution. The consortium reflects the EU Strategy for the Danube Region Strategy (2010), which identified 11 thematic Priority Areas - one of which is the environmental risks. Birth cohorts have been established in all other areas of Europe and collaborative efforts in promoting maternal and fetal health by minimizing the environmental exposures have been initiated with national, European, and international financial support. A birth cohort in the Danube area could apply the established methodologies for prenatal exposure and birth outcome measurements and establish a platform for targeted health promotion in couples planning pregnancies. The consortium included a strong socioeconomic part focusing on the participant's active registration of exposures to environmental toxicants and health indicators of disease and wellbeing, combined with investigation of their risk-reducing behavior and interventions to change their lifestyle to avoid the adverse health risks. Willingness to pay for reducing the health risks in children is also proposed to be estimated. Further collaboration and networking is encouraged as the Danube region has several decades of experience and expertise in biomonitoring adult populations exposed environmentally or occupationally. Additionally, some countries in the Danube region launched small-scale birth cohorts encouraged by participation in several ongoing research projects.

摘要

2013年至2015年期间,欧洲科学家联盟“新多瑙河”成立,旨在多瑙河地区建立一个出生队列,该地区包括欧洲大部分空气污染最严重的国家,面积占欧盟领土的五分之一,涵盖14个国家(9个欧盟成员国),有超过1亿居民,面临诸多挑战:巨大的社会经济差距以及特定区域的环境污染。该联盟体现了《欧盟多瑙河地区战略(2010)》,该战略确定了11个主题优先领域,其中之一是环境风险。欧洲所有其他地区都已建立出生队列,并在国家、欧洲和国际财政支持下,为通过尽量减少环境暴露来促进母婴健康开展了合作努力。多瑙河地区的出生队列可以应用已确立的产前暴露和出生结局测量方法,并为计划怀孕的夫妇建立一个有针对性的健康促进平台。该联盟包括一个强大的社会经济部分,重点是参与者对环境毒物暴露和疾病及健康状况的健康指标进行主动登记,同时调查他们的降低风险行为以及为改变生活方式以避免不良健康风险而采取的干预措施。还提议估计为降低儿童健康风险愿意支付的费用。由于多瑙河地区在对环境或职业暴露的成年人群进行生物监测方面有几十年的经验和专业知识,因此鼓励进一步开展合作与建立网络联系。此外,多瑙河地区的一些国家在参与几个正在进行的研究项目的推动下,启动了小规模的出生队列。

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