Bjornestad Jone, Joa Inge, Larsen Tor K, Langeveld Johannes, Davidson Larry, Ten Velden Hegelstad Wenche, Anda Liss G, Veseth Marius, Melle Ingrid, Johannessen Jan O, Bronnick Kolbjorn
Tidlig Oppdagelse og Behandling av Psykoser - Centre for Clinical Research in Psychosis, Stavanger University HospitalStavanger, Norway; Network for Medical Sciences, University of StavangerStavanger, Norway.
Tidlig Oppdagelse og Behandling av Psykoser - Centre for Clinical Research in Psychosis, Stavanger University HospitalStavanger, Norway; Section of Psychiatry, Department of Clinical Medicine, University of BergenBergen, Norway.
Front Psychol. 2016 Oct 4;7:1491. doi: 10.3389/fpsyg.2016.01491. eCollection 2016.
Predictors of long-term symptomatic remission are crucial to the successful tailoring of treatment in first episode psychosis. There is lack of studies distinguishing the predictive effects of different social factors. This prevents a valid evaluating of their independent effects. To test specific social baseline predictors of long-term remission. We hypothesized that first, satisfaction with social relations predicts remission; second, that frequency of social interaction predicts remission; and third, that the effect of friend relationship satisfaction and frequency will be greater than that of family relations satisfaction and frequency. A sample of first episode psychosis ( = 186) completed baseline measures of social functioning, as well as clinical assessments. We compared groups of remitted and non-remitted individuals using generalized estimating equations analyses. Frequency of social interaction with friends was a significant positive predictor of remission over a two-year period. Neither global perceived social satisfaction nor frequency of family interaction showed significant effects. The study findings are of particular clinical importance since frequency of friendship interaction is a possibly malleable factor. Frequency of interaction could be affected through behavioral modification and therapy already from an early stage in the course, and thus increase remission rates.
首发精神病长期症状缓解的预测因素对于成功制定个体化治疗方案至关重要。目前缺乏区分不同社会因素预测作用的研究。这使得无法有效评估它们的独立作用。为了测试长期缓解的特定社会基线预测因素。我们假设,第一,社会关系满意度可预测缓解;第二,社会交往频率可预测缓解;第三,朋友关系满意度和频率的影响将大于家庭关系满意度和频率的影响。一个首发精神病样本(n = 186)完成了社会功能的基线测量以及临床评估。我们使用广义估计方程分析比较了缓解组和未缓解组个体。在两年期间,与朋友的社会交往频率是缓解的显著正向预测因素。总体感知社会满意度和家庭交往频率均未显示出显著影响。该研究结果具有特殊的临床重要性,因为友谊交往频率是一个可能具有可塑性的因素。交往频率可能从病程早期就可通过行为改变和治疗受到影响,从而提高缓解率。