López-Muñoz Eunice, Ibarra-Avalos Jorge Antonio, Chan-Verdugo Rosario Guadalupe, Mateos-Sánchez Leovigildo, Sánchez-Rodríguez Olivia
a Unidad de Investigación Médica en Medicina Reproductiva, Coordinación de Investigación en Salud, Instituto Mexicano del Seguro Social, Laboratorio K, Colonia Tizapan San Angel, Delegación Álvaro Obregón , Ciudad de México.
b Servicio de Obstetricia, Unidad Médica de Alta Especialidad, Hospital de Gineco Obstetricia No. 4 Luis Castelazo Ayala, Instituto Mexicano del Seguro Social , Ciudad de México.
J Obstet Gynaecol. 2016 Nov;36(8):1069-1075. doi: 10.1080/01443615.2016.1196482. Epub 2016 Oct 20.
In order to determine the prevalence of overt and subclinical hypothyroidism, and isolated hypothyroxinemia during pregnancy, thyroid hormone reference values established by UMAE HGO4, IMSS in Mexico City and those suggested by the American Thyroid Association (ATA) were used. All pregnant patients, whose thyroid function was measured and whose pregnancy was monitored and resolved in UMAE HGO4, IMSS from 1 January to 31 December 2013, were included. Significant differences (p = .00419) were observed in the frequency of subclinical hypothyroidism, being higher when using ATA criteria (18.21% vs. 9.66%). The prevalence rate (UMAE HGO4 vs. ATA) for overt hypothyroidism was 1.11 vs. 1.63, for subclinical hypothyroidism 0.84 vs. 1.41 and for isolated hypothyroxinemia 3.17 vs. 2.79 per 1000 consults during the study period. Independently of prevalence rate, it is essential to provide information on the possible risks involved in pregnancy to all women of childbearing age at the time of hypothyroidism diagnosis.