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产瘫性臂丛神经麻痹患儿持续性残疾的危险因素。

Risk factors for persistent disability in children with obstetric brachial plexus palsy.

作者信息

Zuarez-Easton S, Zafran N, Garmi G, Hasanein J, Edelstein S, Salim R

机构信息

Department of Obstetrics and Gynecology, Emek Medical Center, Afula, Israel.

Rappaport Faculty of Medicine, Technion, Haifa, Israel.

出版信息

J Perinatol. 2017 Feb;37(2):168-171. doi: 10.1038/jp.2016.195. Epub 2016 Oct 20.

Abstract

OBJECTIVE

Obstetric brachial plexus palsy (OBPP) at birth, is a serious neurologic injury that may lead to a long lasting disability. We aimed to examine the occurrence and risk factors associated with disability lasting >1 year.

STUDY DESIGN

A retrospective cohort study conducted between 1993 and 2012 included individuals with diagnosis of OBPP at birth. Affected individual's motor function was evaluated by a direct physical exam based on a muscle grading system of the limb, shoulder, elbow and hand. When not feasible a telephone questionnaire was used. Participants reported on activities of daily living, disability duration and any type of intervention. Stepwise logistic regression model was used to identify demographic and obstetric risk factors for disability lasting >1 year.

RESULTS

Of all 83 806 deliveries during this period, 144 OBPP cases were identified (1.7/1000). Of the 91 (63.2%) individuals located 42 (46.2%) were evaluated by a physical exam and 49 (53.8%) answered a telephone questionnaire. In 12 (13.2%) disability lasted >1 year. Significant predictors for disability lasting >1 year included birthweight >4 kg (P=0.02; odds ratio (OR) 6.17; 95% confidence interval (CI) 1.33-28.65) and younger maternal age (P=0.02; OR 0.84; 95% CI: 0.73-0.97). OBPP decreased 16% per 1 year increase in maternal age.

CONCLUSIONS

OBPP is a transient injury in most cases. Birthweight over 4 kg and younger maternal age maybe associated with disability lasting >1 year.

摘要

目的

出生时的产科臂丛神经麻痹(OBPP)是一种严重的神经损伤,可能导致长期残疾。我们旨在研究持续超过1年的残疾的发生率及相关危险因素。

研究设计

一项回顾性队列研究,研究对象为1993年至2012年间出生时被诊断为OBPP的个体。通过基于肢体、肩部、肘部和手部肌肉分级系统的直接体格检查来评估受影响个体的运动功能。若无法进行体格检查,则使用电话调查问卷。参与者报告日常生活活动、残疾持续时间及任何类型的干预措施。采用逐步逻辑回归模型来确定持续超过1年的残疾的人口统计学和产科危险因素。

结果

在此期间的83806例分娩中,共确诊144例OBPP病例(1.7/1000)。在找到的91例(63.2%)个体中,42例(46.2%)接受了体格检查,49例(53.8%)回答了电话调查问卷。12例(13.2%)残疾持续超过1年。持续超过1年的残疾的显著预测因素包括出生体重>4 kg(P = 0.02;比值比(OR)6.17;95%置信区间(CI)1.33 - 28.65)和母亲年龄较小(P = 0.02;OR 0.84;95% CI:0.73 - 0.97)。母亲年龄每增加1岁,OBPP发生率降低16%。

结论

在大多数情况下,OBPP是一种短暂性损伤。出生体重超过4 kg和母亲年龄较小可能与持续超过1年的残疾有关。

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