Guo Dong, Gong Jianfeng, Cao Lei, Wei Yao, Guo Zhen, Zhu Weiming
Department of General Surgery, Jinling Hospital, Medical School of Nanjing University, No. 305 East Zhongshan Road, Nanjing 210002, China.
Gastroenterol Res Pract. 2016;2016:5264089. doi: 10.1155/2016/5264089. Epub 2016 Sep 29.
. The study aimed to investigate the impact of laparoscopic surgery and open surgery on postoperative edema in Crohn's disease. . Patients who required enterectomy were divided into open group (Group O) and laparoscopic group (Group L). Edema was measured using bioelectrical impedance analysis preoperatively (PRE) and on postoperative day 3 (POD3) and postoperative day 5 (POD5). The postoperative edema was divided into and by an edema index, defined as the ratio of total extracellular water to total body water. . Patients who underwent laparoscopic surgery had better clinical outcomes and lower levels of inflammatory and stress markers. A total of 31 patients (26.05%) developed and 53 patients (44.54%) developed on POD3. More patients developed postoperative edema in Group O than in Group L on POD3 ( = 0.006). The value of the edema index of Group O was higher than that of Group L on POD3 and POD5 (0.402 ± 0.010 versus 0.397 ± 0.008, = 0.001; 0.401 ± 0.009 versus 0.395 ± 0.007, = 0.039, resp.). . Compared with open surgery, laparoscopic surgery can reduce postoperative edema, which may contribute to the better outcomes of laparoscopic surgery over open surgery.
该研究旨在调查腹腔镜手术和开放手术对克罗恩病术后水肿的影响。需要进行肠切除术的患者被分为开放手术组（O组）和腹腔镜手术组（L组）。术前（PRE）、术后第3天（POD3）和术后第5天（POD5）使用生物电阻抗分析测量水肿情况。术后水肿根据水肿指数分为[此处原文缺失具体分类内容]，水肿指数定义为细胞外液总量与总体液量的比值。接受腹腔镜手术的患者临床结局更好，炎症和应激标志物水平更低。共有31例患者（26.05%）在POD3出现[此处原文缺失具体内容]，53例患者（44.54%）在POD3出现[此处原文缺失具体内容]。在POD3时，O组发生术后水肿的患者比L组更多（P = 0.006）。在POD3和POD5时，O组的水肿指数值高于L组（分别为0.402±0.010对0.397±0.008，P = 0.001；0.401±0.009对0.395±0.007，P = 0.039）。与开放手术相比，腹腔镜手术可减轻术后水肿，这可能是腹腔镜手术比开放手术结局更好的原因。
