Laparoscopic Surgery Can Reduce Postoperative Edema Compared with Open Surgery.

. The study aimed to investigate the impact of laparoscopic surgery and open surgery on postoperative edema in Crohn's disease. . Patients who required enterectomy were divided into open group (Group O) and laparoscopic group (Group L). Edema was measured using bioelectrical impedance analysis preoperatively (PRE) and on postoperative day 3 (POD3) and postoperative day 5 (POD5). The postoperative edema was divided into and by an edema index, defined as the ratio of total extracellular water to total body water. . Patients who underwent laparoscopic surgery had better clinical outcomes and lower levels of inflammatory and stress markers. A total of 31 patients (26.05%) developed and 53 patients (44.54%) developed on POD3. More patients developed postoperative edema in Group O than in Group L on POD3 ( = 0.006). The value of the edema index of Group O was higher than that of Group L on POD3 and POD5 (0.402 ± 0.010 versus 0.397 ± 0.008, = 0.001; 0.401 ± 0.009 versus 0.395 ± 0.007, = 0.039, resp.). . Compared with open surgery, laparoscopic surgery can reduce postoperative edema, which may contribute to the better outcomes of laparoscopic surgery over open surgery.