不同生物反应器条件下的杂交瘤细胞培养和聚糖谱数据集。
Hybridoma cell-culture and glycan profile dataset at various bioreactor conditions.
作者信息
Bhatia Hemlata, Read Erik, Agarabi Cyrus, Brorson Kurt, Lute Scott, Yoon Seongkyu
机构信息
Department of Chemical Engineering, University of Massachusetts Lowell, Lowell, MA, USA.
Division II, Office of Biotechnology Products, Office of Pharmaceutical Quality, CDER, FDA, Silver Springs, MD, USA.
出版信息
Data Brief. 2016 Oct 13;9:676-678. doi: 10.1016/j.dib.2016.10.003. eCollection 2016 Dec.
This is an "11 factor-2 level-12 run" Plackett-Burman experimental design dataset. The dataset includes 11 engineering bioreactor parameters as input variables. These 11 factors were varied at 2 levels and 23 response variables that are glycan profile attributes, were measured "A Design Space Exploration for Control of Critical Quality Attributes of mAb" (H. Bhatia, E.K. Read, C.D. Agarabi, K.A. Brorson, S.C. Lute, S. Yoon S, 2016) [2].
这是一个“11因素-2水平-12次运行”的Plackett-Burman实验设计数据集。该数据集包含11个工程生物反应器参数作为输入变量。这11个因素在2个水平上变化，并测量了23个作为聚糖谱属性的响应变量，“单克隆抗体关键质量属性控制的设计空间探索”（H. Bhatia、E.K. Read、C.D. Agarabi、K.A. Brorson、S.C. Lute、S. Yoon S，2016年）[2]。
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