体外肺支持
Extracorporeal lung support.
作者信息
Salna Michael, Bacchetta Matthew
机构信息
aColumbia University College of Physicians and Surgeons bDivision of Cardiothoracic Surgery, Department of Surgery, Columbia University College of Physicians and Surgeons/NewYork-Presbyterian Hospital, New York, New York, USA.
出版信息
Curr Opin Anaesthesiol. 2017 Feb;30(1):50-57. doi: 10.1097/ACO.0000000000000415.
PURPOSE OF REVIEW
The applications for extracorporeal membrane oxygenation for lung support are constantly evolving. This review highlights fundamental concepts in extracorporeal lung support and describes directions for future research.
RECENT FINDINGS
Since the 1950s, extracorporeal lung support has experienced continuous advancements in circuit design and safety in acute respiratory distress syndrome, chronic obstructive pulmonary disease exacerbations, as a bridge to transplantation, intraoperative cardiopulmonary support, and for transportation to referral centers. Patients on extracorporeal membrane oxygenation are now capable of being awake, extubated, and ambulatory for accelerated recovery or optimization for transplantation.
SUMMARY
Extracorporeal lung support is a safe and an easily implemented intervention for refractory respiratory failure. Recent advances have extended its use beyond acute illnesses and the developments for chronic support will facilitate the development of durable devices and possible artificial lung development.
综述目的
体外膜肺氧合在肺支持方面的应用不断发展。本综述重点介绍体外肺支持的基本概念，并描述未来研究方向。
最新发现
自20世纪50年代以来，体外肺支持在急性呼吸窘迫综合征、慢性阻塞性肺疾病急性加重、作为移植桥梁、术中心肺支持以及转运至转诊中心等方面，在回路设计和安全性上不断取得进展。接受体外膜肺氧合治疗的患者现在能够保持清醒、拔管并可活动，以加速康复或优化移植条件。
总结
体外肺支持是一种用于难治性呼吸衰竭的安全且易于实施的干预措施。最近的进展已将其应用扩展到急性疾病之外，慢性支持方面的发展将推动耐用设备的开发以及可能的人工肺的发展。
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