Sánchez Jorge, Sánchez Andrés, Cardona Ricardo
Universidad de Antioquia, Grupo de Alergología Clínica y Experimental, IPS Universitaria. Medellín, Colombia.
Rev Alerg Mex. 2016 Oct-Dec;63(4):323-333. doi: 10.29262/ram.v63i4.238.
Allergen immunotherapy has proved effective in the treatment of various allergies, but whether the clinical benefits outweigh the economic costs has been little evaluated.
To explore the economic consequences of immunotherapy in asthma, rhinitis and dermatitis.
Descriptive study. Patients with at least 18 months' follow-up were selected, whose medical history allowed evaluation of drugs received, manner of use, check-ups, treatment changes, reasons for these, and so on. Patients were classified according to whether they received drug treatment + immunotherapy (active group) or drug therapy alone (control group).
1848 patients were included: 648 in the active group and 1200 in the control. Immunotherapy increased the cost of treatment during the first few months, but after 9 to 12 months drug treatment decreased significantly compared to the control group. In patients with asthma or various diseases, immunotherapy reduced costs of treatment (p < 0.05). The active group saw fewer relapses at 18 months (p < 0.05).
Allergen immunotherapy allows the sustained reduction in drug treatment, with medium-term financial savings for the patient and the health system.
变应原免疫疗法已被证明在治疗各种过敏症方面有效,但临床益处是否超过经济成本却很少得到评估。
探讨免疫疗法在哮喘、鼻炎和皮炎治疗中的经济后果。
描述性研究。选择随访至少18个月的患者,其病史允许评估所接受的药物、使用方式、检查、治疗变化及其原因等。根据患者是接受药物治疗+免疫疗法(治疗组)还是仅接受药物治疗(对照组)进行分类。
共纳入1848例患者:治疗组648例,对照组1200例。免疫疗法在最初几个月增加了治疗成本,但9至12个月后,与对照组相比,药物治疗成本显著降低。在患有哮喘或多种疾病的患者中,免疫疗法降低了治疗成本(p<0.05)。治疗组在18个月时复发较少(p<0.05)。
变应原免疫疗法可使药物治疗持续减少,为患者和卫生系统节省中期费用。