从意大利罗马的糖尿病患者中分离出的[相关物质]的基因型和表型异质性。 （注：原文中“Genotypic and phenotypic heterogeneity in isolated from”表述不完整，推测是某种物质被从糖尿病患者中分离出来，但具体是什么物质缺失，这里按补充完整后的意思翻译）
Genotypic and phenotypic heterogeneity in isolated from diabetic patients in Rome, Italy.
作者信息
De Arpan, Pasquantonio Guido, Cerroni Loredana, Petrelli Dezemona, Lauro Davide, Longhi Marta, Vitali Luca A
机构信息
Microbiology Unit, School of Pharmacy, University of Camerino, Via Gentile III da Varano, 62032 Camerino, MC Italy.
Department of Clinical Science and Translational Medicine, University of Rome Tor Vergata, Rome, Italy.
出版信息
Springerplus. 2016 Oct 13;5(1):1794. doi: 10.1186/s40064-016-3470-0. eCollection 2016.
Our study focuses on the antimicrobial susceptibility, genotypic and phenotypic heterogeneity, and serotype classification of the isolated from type II diabetic patients (n = 25; age 42-68). Eighty-two percent of isolates were classified as serotype . No serotype was present. Macrorestriction analysis of genomic DNA of the isolates exhibited a clonal diversity that paralleled the phenotypic heterogeneity, which was also assessed in terms of biofilm forming ability. Isolates were susceptible to all the classes of antibiotics. In conclusion a great heterogeneity and no antimicrobial resistance were apparent in the considered strains from diabetic patients.
我们的研究聚焦于从II型糖尿病患者（n = 25；年龄42 - 68岁）中分离出的菌株的抗菌药敏性、基因型和表型异质性以及血清型分类。82%的分离菌株被归类为血清型 。不存在血清型 。对分离菌株基因组DNA的宏观限制性分析显示出与表型异质性平行的克隆多样性，表型异质性也根据生物膜形成能力进行了评估。分离菌株对所有种类的抗生素均敏感。总之，在考虑的糖尿病患者菌株中，明显存在很大的异质性且无抗菌耐药性。
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