Nicolescu Mihnea Ioan
Histology and Cytology Department, "Carol Davila" University of Medicine and Pharmacy, 8 Eroilor Sanitari, RO-050474, Bucharest, Romania.
"Victor Babeș" National Institute of Pathology, Bucharest, Romania.
Adv Exp Med Biol. 2016;913:163-176. doi: 10.1007/978-981-10-1061-3_11.
Stroma is viewed as the supportive framework of a predominant epithelial organ, comprising mostly of connective tissue, blood vessels and nerves. Since the discovery of telocytes one decade ago (Popescu and Faussone-Pellegrini J Cell Mol Med 2010;14(4):729-40), their presence was proven in several exocrine gland stromata, including major and minor salivary glands, mammary glands as well as exocrine pancreas.Telocytes have been found in a close connection with acinar and ductal structures but also with their stromal neighbours - nerves, blood vessels or other connective elements, either cells or collagen fibres.The approaches used to reveal the telocytes' location were immunohistochemistry and electron microscopy.
间质被视为主要上皮器官的支持框架，主要由结缔组织、血管和神经组成。自十年前发现端细胞以来（Popescu和Faussone-Pellegrini，《细胞与分子医学杂志》，2010年；14(4):729 - 40），已在多个外分泌腺间质中证实了它们的存在，包括大、小唾液腺、乳腺以及外分泌胰腺。已发现端细胞与腺泡和导管结构密切相关，也与它们的间质邻居——神经、血管或其他结缔成分（细胞或胶原纤维）密切相关。用于揭示端细胞位置的方法是免疫组织化学和电子显微镜。
