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老年患者头颈部坏死性牙源性筋膜炎累及前纵隔:创新治疗并文献复习

Necrotizing odontogenic fasciitis of head and neck extending to anterior mediastinum in elderly patients: innovative treatment with a review of the literature.

作者信息

Cortese Antonio, Pantaleo Giuseppe, Borri Antonio, Amato Massimo, Claudio Pier Paolo

机构信息

Unit of Maxillofacial Surgery, Department of Medicine and Surgery, University of Salerno, Via S. Allende, 84081, Baronissi, SA, Italy.

Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, Naples, Italy.

出版信息

Aging Clin Exp Res. 2017 Feb;29(Suppl 1):159-165. doi: 10.1007/s40520-016-0650-2. Epub 2016 Oct 31.

Abstract

BACKGROUND

Necrotizing fasciitis (NF) of odontogenic origin affecting the head and neck region is a rare but serious clinical condition, which, if diagnosed late, can lead to a fatal outcome. The early diagnosis of necrotizing fasciitis can be difficult. Delay in diagnosis leads to increase in the area of necrosis with a resulting increase in cosmetic deformity and life-threatening complication. In this study, we present two cases of elderly patients with aggressive NF affecting the neck and anterior mediastinum, which were of odontogenic origin.

METHODS

In the two patients selected necrotic skin and soft tissue were removed and wide exposure was achieved with debridement of the neck at the level of the affected layer of superficial cervical fascia. Saline solution was used as irrigation to treat the patients with acute necrotizing fasciitis. Difficulties in managing this condition with NF extent to deep anterior mediastinum is related to clavicle osteotomy or thoracotomy need with high surgical risks. In our technique, by gentle suction in anterior mediastinum, necrotic tissue resection was possible without any osteotomy need.

CONCLUSIONS

Suctioning resection technique associated with hyperbaric, metabolic rebalance, and amino acid support in association with three types antibiotic therapy are fundamental points for correct therapy strategy, leading to full recovery and healing of NF patients even if in very unfavorable conditions. Multidisciplinary approach is paramount for proper treatment of this disease.

摘要

背景

牙源性坏死性筋膜炎(NF)累及头颈部是一种罕见但严重的临床病症,若诊断延迟,可能导致致命后果。坏死性筋膜炎的早期诊断可能具有挑战性。诊断延迟会导致坏死面积增加,进而导致美容畸形加剧和危及生命的并发症。在本研究中,我们呈现了两例侵袭性NF累及颈部和前纵隔的老年患者病例,其病因源自牙源性。

方法

在所选的两名患者中,切除坏死的皮肤和软组织,并在颈浅筋膜受累层面进行颈部清创以实现广泛暴露。使用生理盐水冲洗治疗急性坏死性筋膜炎患者。对于NF累及前纵隔深部的病情处理困难,这与需要进行锁骨截骨术或开胸手术且手术风险高有关。在我们的技术中,通过在前纵隔进行轻柔吸引,可以在无需任何截骨术的情况下切除坏死组织。

结论

与高压氧、代谢平衡和氨基酸支持相结合的吸引切除技术,以及三种类型的抗生素治疗,是正确治疗策略的基本要点,即使在非常不利的情况下,也能使NF患者完全康复并愈合。多学科方法对于正确治疗这种疾病至关重要。

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