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[扩展振荡阻力测定法——一种用于研究肺功能测试的独立方法]

[Expanded oscillo-resistometry--an independent method for studying lung function tests].

作者信息

Sebastiani O

出版信息

Pneumologie. 1989 Jul;43(7):363-8.

PMID:2780529
Abstract

The lung is a complicated organ, both physiologically and from the point of view of carrying out measurements. The tissue is elastic, as also is the enclosed air. Since the alveolar pressure cannot be measured directly, various component factors or resistances are measured. While whole-body plethysmography measures almost exclusively the actual flow or airway resistance, the forced oscillation technique measures the acoustic resistance of the entire respiratory tract. Although the two methods correlate to a high degree, considered objectively, they are unable to produce identical results. The forced oscillation technique must be considered a separate measuring method, which belongs in the area for which it was developed - in the office of the privately practising internist or general practitioner. If the forced oscillation technique provides the physician with a technically simple method which does not put any stress on the patient, and which, quickly and largely independently of the cooperation of the patient, is capable of accurately differentiating or quantitatively assessing pulmonary emphysema and endobronchial obstruction - that is, the pulmonary diseases that are by far and away the most common - it will already have fulfilled a very important requirement. Pneumologists attach great diagnostic significance to the Ros-respiratory volume curve and the phase angle. While the physician is already able to interpret the Ros curve in terms of the pathological state of the patient, the significance of the phase angle still needs to be investigated in more detail. In addition, it must be confirmed that the forced oscillation technique reacts sensitively to, for example, the administration of theophylline, and established whether, in patients with allergic diseases, it can reveal early changes that might escape detection by whole-body plethysmography.

摘要

肺是一个复杂的器官,无论是在生理方面,还是从进行测量的角度来看。肺组织具有弹性,其中所含的空气也是如此。由于肺泡压力无法直接测量,因此需测量各种组成因素或阻力。全身体积描记法几乎专门用于测量实际流量或气道阻力,而强迫振荡技术则测量整个呼吸道的声阻。尽管这两种方法具有高度相关性,但客观地说,它们无法得出完全相同的结果。强迫振荡技术必须被视为一种独立的测量方法,它属于其开发的领域——私人执业内科医生或全科医生的诊所。如果强迫振荡技术能为医生提供一种技术上简单的方法,这种方法不会给患者带来任何压力,并且能够快速且在很大程度上独立于患者的配合,准确地区分或定量评估肺气肿和支气管内阻塞——即目前最常见的肺部疾病——那么它就已经满足了一项非常重要的要求。肺病专家非常重视罗斯呼吸容积曲线和相角。虽然医生已经能够根据患者的病理状态来解释罗斯曲线,但相角的意义仍需要更详细地研究。此外,必须确认强迫振荡技术对例如给予茶碱有敏感反应,并确定在患有过敏性疾病的患者中,它是否能揭示全身体积描记法可能无法检测到的早期变化。

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1
[Expanded oscillo-resistometry--an independent method for studying lung function tests].[扩展振荡阻力测定法——一种用于研究肺功能测试的独立方法]
Pneumologie. 1989 Jul;43(7):363-8.
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