El Douaihy Youssef, Krzyzak Michael, Barakat Iskandar, Deeb Liliane
Department of Internal Medicine, Staten Island University Hospital, Staten Island, NY.
Department of Gastroenterology, Staten Island University Hospital, Staten Island, NY.
ACG Case Rep J. 2016 Aug 17;3(4):e99. doi: 10.14309/crj.2016.72. eCollection 2016 Aug.
Patients with superficial bladder cancers remain clinically indolent after treatment with even a modicum of urologic intervention. However, with more invasive disease, the majority of patients experience recurrence. The conventional route of metastasis and recurrence in primary urothelial cell carcinoma is through lymphatic system, with regional lymph nodes, lungs, liver, brain, and bone being the most common sites. Isolated intraluminal colonic recurrence in the absence of local invasion is extremely rare. We report a unique case of urothelial cell carcinoma presenting with an isolated colonic mass, which unexpectedly, on immunohistostaining, proved to be primarily of urothelial rather than colonic origin.
浅表性膀胱癌患者即使接受了少量的泌尿外科干预治疗后,临床症状仍呈惰性。然而,对于侵袭性更强的疾病,大多数患者会出现复发。原发性尿路上皮细胞癌转移和复发的传统途径是通过淋巴系统,区域淋巴结、肺、肝、脑和骨是最常见的部位。在没有局部侵犯的情况下,孤立的腔内结肠复发极为罕见。我们报告了一例独特的尿路上皮细胞癌病例,表现为孤立的结肠肿块,出乎意料的是,免疫组化结果显示其主要起源于尿路上皮而非结肠。