Kulkarni Geeta, Liu Xiuli, Shen Bo
Department of Gastroenterology/Hepatology, Cleveland Clinic Foundation, Cleveland, OH.
Department of Anatomic Pathology, Cleveland Clinic Foundation, Cleveland, OH.
ACG Case Rep J. 2016 Sep 28;3(4):e129. doi: 10.14309/crj.2016.102. eCollection 2016 Aug.
Radiation therapy is a viable option in managing potentially life-threatening malignancies including prostate cancer. It is known that pelvic radiation can result in injury of the distal large bowel with the development of radiation proctitis. Despite reports from retrospective studies, there is a lack of direct endoscopic and histologic evidence of external pelvic radiation injury to the ileal pouch-anal anastomosis. We present a case of a 68-year-old male with pouchitis resulting from pelvic radiation for prostate cancer.
放射治疗是治疗包括前列腺癌在内的潜在危及生命的恶性肿瘤的一种可行选择。众所周知,盆腔放疗可导致远端大肠损伤并引发放射性直肠炎。尽管有回顾性研究报告,但缺乏盆腔外照射对回肠袋肛管吻合术造成损伤的直接内镜和组织学证据。我们报告一例68岁男性因前列腺癌盆腔放疗导致袋炎的病例。