一种用于筛查严重先天性心脏病的新型、更高效的分阶段方法。
A novel, more efficient, staged approach for critical congenital heart disease screening.
作者信息
Mouledoux J, Guerra S, Ballweg J, Li Y, Walsh W
机构信息
Department of Pediatrics, Oschner Medical Center, New Orleans, LA, USA.
Tennessee Department of Health, Andrew Johnson Tower, Nashville, TN, USA.
出版信息
J Perinatol. 2017 Mar;37(3):288-290. doi: 10.1038/jp.2016.204. Epub 2016 Nov 10.
OBJECTIVE
Screening for critical congenital heart disease (CCHD) using pulse oximetry has been endorsed by the American Academy of Pediatrics and the American Heart Association. The recommended screening requires two saturation readings. We sought to determine the incidence of undetected CCHD in Tennessee for the 2 years following implementation of an algorithm that assigned an immediate pass to a single lower extremity saturation of 97% or higher.
STUDY DESIGN
State Genetic Screening records and reports of missed cases from the Tennessee Initiative for Perinatal Quality Care were used to determine if CCHD cases were missed by the new screening algorithm.
RESULT
During the study, 232 infants failed the screen with 51 or 22% true positives, 13 infants had undetected CCHD (10 coarctations, 2 anomalous veins and 1 Tetralogy of Fallot).
CONCLUSION
This approach eliminated over 150 000 pulse oximetry determinations in Tennessee without affecting the ability of pulse oximetry to detect CCHD before discharge.
目的
使用脉搏血氧饱和度仪筛查严重先天性心脏病(CCHD)已得到美国儿科学会和美国心脏协会的认可。推荐的筛查需要进行两次饱和度读数。我们试图确定在田纳西州实施一种算法后的两年内未被检测出的CCHD的发生率,该算法将单次下肢饱和度为97%或更高的情况立即判定为通过。
研究设计
利用田纳西州围产期质量护理倡议的州基因筛查记录和漏诊病例报告,来确定新的筛查算法是否漏诊了CCHD病例。
结果
在研究期间,232名婴儿筛查未通过,其中51名(22%)为真阳性,13名婴儿的CCHD未被检测出(10例主动脉缩窄、2例异常静脉和1例法洛四联症)。
结论
这种方法在田纳西州消除了超过150000次脉搏血氧饱和度测定,同时不影响脉搏血氧饱和度仪在出院前检测CCHD的能力。
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