Rensing Nicholas, Waterman Brian R, Frank Rachel M, Heida Kenneth A, Orr Justin D
Department of Orthopaedic Surgery and Rehabilitation, William Beaumont Army Medical Center, El Paso, Texas (NR, BRW, KAH, JDO).
Rush University Medical Center, Chicago, Illinois (RMF).
Foot Ankle Spec. 2017 Jun;10(3):216-226. doi: 10.1177/1938640016676340. Epub 2016 Nov 11.
Historically, Achilles tendon repairs and other surgeries about the hindfoot have demonstrated a significantly higher rate of wound healing complications and surgical site morbidity. The purpose of this study was to evaluate the comprehensive complication profile and risk factors for adverse short-term, clinical outcomes after primary repair of Achilles tendon ruptures.
Between the years 2005 and 2014, all cases of primary Achilles tendon repair (Current Procedural Terminology code 27650) entered into the National Surgical Quality Improvement Project (NSQIP) database were extracted for analysis. Primary outcomes of interest were rates of total complication, reoperation, and rerupture within 30 days of index surgery. Independent risk factors associated with these selected endpoints were assessed with chi-square and logistic regression analysis and odds ratios with 95% confidence intervals were used to express relative risk.
Of 1626 patients with an average age of 44 years (SD 13.3), the average ASA classification was 1.69 and hypertension (20.7%), morbid obesity (8.3%), and diabetes (4.9%) were among the most common medical comorbidities. A total of 28 (1.7%) patients sustained perioperative complications, including 1.3% with local complications (0.7% superficial wound infection, 0.4% wound disruption) and no cases of peripheral nerve injury or early repair failure. Systemic complications occurred in 0.4%, most commonly with deep venous thrombosis or nonfatal thromboembolism. Preoperative albumin was independently associated with an increased risk of local wound complications (odds ratio [OR] 28.67; 95% CI 1.42-579.40; P = .029). Chronic obstructive pulmonary disease (OR 22.33, 95% CI 2.49-199.81; P = .006) and bleeding disorder (OR 14.83, 95% CI 1.70-129.50; P = .015) were more likely to result in a systemic complication, and preoperative creatinine correlated with an increased risk of any complication (OR 6.11, 95% CI 1.15-32.34; P = .033). In total there were 5 (0.3%) readmissions with 2 (0.1%) unplanned reoperations attributed to local wound complications.
Among a broad-based demographic of the United States, the rate of local wound complications was exceedingly low in the short-term perioperative period, although this risk may be significantly magnified with subtle decreases in albumin levels. Preoperative risk stratifications should carefully scrutinize for subtle abnormalities in nutritional parameters and renal function prior to undergoing Achilles surgery.
Therapeutic, Level II: Prospective, comparative trial.
从历史上看,跟腱修复术及其他后足手术的伤口愈合并发症和手术部位发病率显著更高。本研究的目的是评估跟腱断裂一期修复术后短期临床不良结局的综合并发症情况及危险因素。
提取2005年至2014年录入国家外科质量改进项目(NSQIP)数据库的所有跟腱一期修复病例(当前手术操作术语编码27650)进行分析。感兴趣的主要结局是初次手术后30天内的总并发症发生率、再次手术率和再断裂率。通过卡方检验和逻辑回归分析评估与这些选定终点相关的独立危险因素,并使用95%置信区间的比值比来表示相对风险。
1626例患者的平均年龄为44岁(标准差13.3),平均美国麻醉医师协会(ASA)分级为1.69,最常见的内科合并症包括高血压(20.7%)、病态肥胖(8.3%)和糖尿病(4.9%)。共有28例(1.7%)患者发生围手术期并发症,其中1.3%为局部并发症(0.7%为浅表伤口感染,0.4%为伤口裂开),无周围神经损伤或早期修复失败病例。全身并发症发生率为0.4%,最常见的是深静脉血栓形成或非致命性血栓栓塞。术前白蛋白水平独立与局部伤口并发症风险增加相关(比值比[OR]28.67;95%置信区间1.42 - 579.40;P = 0.029)。慢性阻塞性肺疾病(OR 22.33,95%置信区间2.49 - 199.81;P = 0.006)和出血性疾病(OR 14.83,95%置信区间1.70 - 129.50;P = 0.015)更易导致全身并发症,术前肌酐水平与任何并发症风险增加相关(OR 6.11,95%置信区间1.15 - 32.34;P = 0.033)。共有5例(0.3%)患者再次入院,其中2例(0.1%)因局部伤口并发症进行了非计划再次手术。
在美国广泛的人群中,短期围手术期局部伤口并发症发生率极低,尽管白蛋白水平轻微下降可能会显著增加这种风险。在进行跟腱手术前,术前风险分层应仔细筛查营养参数和肾功能的细微异常。
治疗性,二级:前瞻性比较试验。