Mehrpour Omid, Sheikhazadi Ardeshir, Barzegar Afsoon, Husein Afzal, Malic Claudia, Sheikhazadi Elham, Saberi-Anary Seyed Hossein
Associate Professor, Atherosclerosis and Coronary Artery Research Center AND Medical Toxicology and Drug Abuse Research Center, Birjand University of Medical Sciences, Birjand, Iran.
Professor, Toxicology and Poisoning Research Centre AND Department of Forensic Medicine and Toxicology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Addict Health. 2016 Apr;8(2):76-83.
Recreational drugs have a significant impact on the lives of drug users, their close families andfriends, as well as their society. Social, psychological, biological, and genetic factors could make a personmore prone to using recreational drugs. Finger and A-B ridges (dermatoglyphics) are formed during the firstand second trimesters of fetal development, under the influence of environmental and genetic factors. Theaim of our study was to investigate and evaluate a possible link between dermatoglyphics and opium usage.
The pattern of dermatoglyphics - finger and A-B prints - obtained from a group of opium users(121 patients) was compared to those obtained from a group of opium non-users (121 patients) from Birjand,Iran. The results were analyzed using chi-square, t and Mann-Whitney tests.
The results showed that although A-B ridges of palms and fingers in our study group were highercompared to the control group, there was no significant difference between these groups. The only significantdifference was the fingerprint patterns of the left ring finger in the study group, which lacked the arch patternand had less loop patterns. The dominant type of fingerprint in the left ring finger was the whorl. In ouropium user group, the arch and loop fingerprint patterns were heterogeneous and significantly different incomparison with the control group (P < 0.01).
These findings suggest that a genetic factor may increase the predisposition to recreational drugusage. Further research is required to confirm this possible impact of genetic factors on the addiction process.
消遣性药物对吸毒者及其亲密家人、朋友以及他们所处的社会的生活有着重大影响。社会、心理、生物和遗传因素可能使一个人更容易使用消遣性药物。指纹和A - B嵴(皮纹学特征)在胎儿发育的头两个孕期,受环境和遗传因素影响而形成。我们研究的目的是调查和评估皮纹学与鸦片使用之间可能存在的联系。
将从一组鸦片使用者(121例患者)获取的皮纹学特征——指纹和A - B指纹——与从伊朗比尔詹德的一组非鸦片使用者(121例患者)获取的特征进行比较。使用卡方检验、t检验和曼 - 惠特尼检验对结果进行分析。
结果显示,虽然我们研究组手掌和手指的A - B嵴比对照组高,但两组之间没有显著差异。唯一显著的差异是研究组左手无名指的指纹模式,该组缺乏弓型模式且箕型模式较少。左手无名指指纹的主要类型是斗型。在我们的鸦片使用者组中,弓型和箕型指纹模式具有异质性,与对照组相比有显著差异(P < 0.01)。
这些发现表明遗传因素可能增加对消遣性药物使用的易感性。需要进一步研究来证实遗传因素对成瘾过程的这种可能影响。