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静脉和动脉切除在胰腺癌手术中的作用。

The Role of Venous and Arterial Resection in Pancreatic Cancer Surgery.

机构信息

Surgical Outcomes Analysis & Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

Department of Surgery, Ochsner Health System, New Orleans, LA, USA.

出版信息

Ann Surg Oncol. 2018 Jan;25(1):51-58. doi: 10.1245/s10434-016-5676-3. Epub 2016 Nov 23.

Abstract

Pancreatic cancer continues to carry a dismal prognosis with the majority of patients presenting at advanced stages of disease. Complete surgical resection remains essential for prolonging survival and increasing the possibility of cure. However, few patients will be resectable at diagnosis, with a significant portion presenting with borderline or locally advanced disease. The addition of vascular resection and reconstruction at the time of pancreatectomy enables expansion of the patient population able to undergo resection with curative intent and achieve tumor-free margins. This review provides an overview of the literature regarding the role of venous and arterial resection in the treatment of pancreatic cancer, with a focus on outcomes including survival, morbidity, and mortality.

摘要

胰腺癌的预后仍然不容乐观,大多数患者在疾病的晚期才被发现。彻底的手术切除仍然是延长生存时间和提高治愈可能性的关键。然而,在诊断时只有少数患者可以进行手术切除,相当一部分患者表现为边界性或局部晚期疾病。在胰切除术时进行血管切除和重建可以扩大能够进行根治性切除并实现无肿瘤切缘的患者群体。本文综述了关于静脉和动脉切除在胰腺癌治疗中的作用的文献,重点关注包括生存率、发病率和死亡率在内的结果。

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