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胰高血糖素样肽-1及其受体激动剂:它们在2型糖尿病管理中的作用。

Glucagon like peptide-1 and its receptor agonists: Their roles in management of Type 2 diabetes mellitus.

作者信息

Gupta Ankit, Jelinek Herbert F, Al-Aubaidy Hayder

机构信息

School of Medicine, University of Tasmania, Hobart, Australia.

School of Community Health, Charles Sturt University, Albury, NSW, Australia.

出版信息

Diabetes Metab Syndr. 2017 Jul-Sep;11(3):225-230. doi: 10.1016/j.dsx.2016.09.003. Epub 2016 Sep 15.

Abstract

This study summarizes major work which investigated the roles of glucagon like peptide-1 (GLP-1) and its receptor (GLP-1R); the use of GLP-1-R agonists and dipeptidyl peptidase 4 inhibitor in the management of type 2 diabetes mellitus. It focuses on the recent therapeutic development which has occurred in this field, and also discusses the potential treatments which can be discovered and implemented in the near future to design an effective therapy for type 2 diabetes mellitus.

摘要

本研究总结了调查胰高血糖素样肽-1(GLP-1)及其受体(GLP-1R)作用的主要工作;GLP-1受体激动剂和二肽基肽酶4抑制剂在2型糖尿病管理中的应用。它聚焦于该领域最近的治疗进展,还讨论了在不久的将来可能发现并实施的潜在治疗方法,以设计出针对2型糖尿病的有效疗法。

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