Kumar Sunil, Minz Mukut, Sinha Saroj K, Vaiphei Kim, Sharma Ashish, Singh Sarbpreet, Kenwar Deepesh B
Department of Renal Transplant Surgery, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Department of Gastroenterology, PGIMER, Chandigarh, India.
Transpl Infect Dis. 2017 Feb;19(1). doi: 10.1111/tid.12640.
We report a renal allograft transplant recipient with esophageal tuberculosis (TB) coinfected with herpes simplex virus (HSV) and Candida. The patient presented with oropharyngeal candidiasis and was started on fluconazole. Upper gastrointestinal endoscopy showed whitish patches with mucosal ulcers in the esophagus. Histopathological examination confirmed TB and HSV infection. The patient recovered after antiviral, antifungal, and anti-tubercular therapy with reduction in immunosuppression. In a TB-endemic zone, TB can coexist with opportunistic infections in an immunocompromised host.
我们报告了一名肾移植受者,其患有食管结核(TB),同时合并单纯疱疹病毒(HSV)和念珠菌感染。该患者出现口咽念珠菌病,开始使用氟康唑治疗。上消化道内镜检查显示食管有白色斑块及黏膜溃疡。组织病理学检查确诊为结核和HSV感染。患者在接受抗病毒、抗真菌和抗结核治疗并减少免疫抑制后康复。在结核病流行地区,结核病可在免疫功能低下的宿主中与机会性感染并存。