Buchalter Daniel B, Mahure Siddharth A, Mollon Brent, Yu Stephen, Kwon Young W, Zuckerman Joseph D
Department of Orthopaedic Surgery, New York University Langone Medical Center, NYU Hospital for Joint Diseases, New York, NY, USA.
Department of Orthopaedic Surgery, New York University Langone Medical Center, NYU Hospital for Joint Diseases, New York, NY, USA.
J Shoulder Elbow Surg. 2017 Jun;26(6):939-947. doi: 10.1016/j.jse.2016.09.056. Epub 2016 Nov 22.
Periprosthetic shoulder infections (PSIs) are challenging to treat and often result in significant patient morbidity. Without a standardized treatment protocol, PSIs are often managed similarly to periprosthetic hip and knee infections. Because 2-stage revision is the gold standard for treating periprosthetic hip and knee infections, we performed a case series and literature review to determine its effectiveness in PSIs.
We identified 19 patients (14 men) from our institution who were treated with a 2-stage revision after presenting with a PSI. Mean patient age was 63 ± 9 years, and average body mass index was 30.8 ± 5.8. The average time from the index arthroplasty to treatment was 40 months, 8 of 13 positive cultures were Propionibacterium acnes, and 9 of 19 patients had multiple shoulder operations before presenting with infection. Minimum follow-up for all patients was 2 years.
After a mean follow-up of 63 months (range, 25-184 months), 15 of 19 patients in our study were successfully treated for PSI. Average postoperative American Shoulder and Elbow Surgeons (ASES) Shoulder Assessment score was 69 (range, 32-98) and average postoperative forward elevation was significantly increased from 58° to 119° (P < .001). The incidence of recurrent infection was 26%. The rate of noninfection complications was 16%, for a total complication rate of 42%.
In patients with PSIs, especially those with intractable, chronic infections, a 2-stage revision represents a viable treatment option for eradicating infection and restoring function. However, it is important to recognize the risk of recurrent infection and postoperative complications in this challenging patient population.
人工肩关节周围感染(PSIs)的治疗具有挑战性,常常导致患者出现严重的发病情况。由于缺乏标准化的治疗方案,PSIs的治疗方式通常与人工髋关节和膝关节周围感染的治疗方式相似。鉴于两阶段翻修术是治疗人工髋关节和膝关节周围感染的金标准,我们进行了一项病例系列研究和文献综述,以确定其在PSIs治疗中的有效性。
我们从本机构中确定了19例患者(14例男性),这些患者在出现PSIs后接受了两阶段翻修术治疗。患者的平均年龄为63±9岁,平均体重指数为30.8±5.8。从初次关节置换到接受治疗的平均时间为40个月,13份阳性培养物中有8份为痤疮丙酸杆菌,19例患者中有9例在出现感染之前接受过多次肩部手术。所有患者的最短随访时间为2年。
在平均随访63个月(范围为25 - 184个月)后,我们研究中的19例患者中有15例成功治愈了PSIs。术后美国肩肘外科医师学会(ASES)肩关节评估平均得分为69分(范围为32 - 98分),术后平均前屈角度从58°显著增加至119°(P <.001)。复发感染的发生率为26%。非感染性并发症的发生率为16%,总并发症发生率为42%。
对于患有PSIs的患者,尤其是那些患有难治性慢性感染的患者,两阶段翻修术是根除感染和恢复功能的一种可行治疗选择。然而,认识到这一具有挑战性的患者群体中存在复发感染和术后并发症的风险很重要。