Hilschenz Ingo, Ito Yosuke, Natsukawa Hiroaki, Oida Takenori, Yamamoto Tetsuya, Kobayashi Tetsuo
Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan.
Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan.
J Magn Reson. 2017 Jan;274:89-94. doi: 10.1016/j.jmr.2016.11.006. Epub 2016 Nov 18.
Superconducting quantum interference devices are widely used in basic and clinical biomagnetic measurements such as low-field magnetic resonance imaging and magnetoencephalography primarily because they exhibit high sensitivity at low frequencies and have a wide bandwidth. The main disadvantage of these devices is that they require cryogenic coolants, which are rather expensive and not easily available. Meanwhile, with the advances in laser technology in the past few years, optically pumped atomic magnetometers (OPAMs) have been shown to be a good alternative as they can have adequate noise levels and are several millimeters in size, which makes them significantly easier to use. In this study, we used an OPAM module operating at a Larmor frequency of 5kHz to acquire NMR and MRI signals. This study presents these initial results as well as our initial attempts at imaging using this OPAM module. In addition, we have designed a liquid-cooled pre-polarizing coil that reduces the measurement time significantly.
超导量子干涉装置广泛应用于基础和临床生物磁测量,如低场磁共振成像和脑磁图,主要是因为它们在低频下具有高灵敏度且带宽较宽。这些装置的主要缺点是需要低温冷却剂,而低温冷却剂相当昂贵且不易获得。与此同时,随着过去几年激光技术的进步,光泵浦原子磁力仪(OPAM)已被证明是一个很好的替代方案,因为它们可以具有足够的噪声水平,并且尺寸为几毫米,这使得它们使用起来明显更容易。在本研究中,我们使用了一个工作在拉莫尔频率5kHz的OPAM模块来采集核磁共振和磁共振成像信号。本研究展示了这些初步结果以及我们使用该OPAM模块进行成像的初步尝试。此外,我们设计了一种液冷预极化线圈,可显著缩短测量时间。