[The incidence of genital chlamydial infections in patients of a venereologic consultation clinic].

Chlamydia trachomatis represents today's most important agent of genital contact infections. It occurs more frequently than Neisseria gonorrhoeae. A prevalence-study of Chlamydia trachomatis (C.t.) and Neisseria gonorrhoeae (N.g.) among venerological out-patients is presented. C.t. was grown in cycloheximide treated McCoy cell culture, N.g. on human blood agar. Our of 551 patients (321 males, 230 females) C.t. was isolated in 17.8%, whereas N.g. was isolated in 8.5%. The isolation rate for males was estimated as 23% for C.t., 12% for N.g., compared to 5% for C.t. and 2% for N.g. in women. Nearly half of gonococcal infections was accompanied by C.t. (men 42.1%, women 55.6%). Age related, both C.t. and N.g. infections occurred mainly between 21 and 26 years (about 50%). Infection with C.t. occurred earlier than infections with N.g., 16 years and 18 years respectively. The high prevalence of C. trachomatis infection demand some consequences: 1. Extensing the number of diagnostic facilities. 2. Inauguration of new methods (monoclonal antibody-test, enzymimmunoassays). 3. Diagnostic and treatment of sexual partner. 4. Treatment with tetracyclines. 5. Therapy regiment for gonococcal infection: single high dose penicillin combined with probenicide followed by tetracycline therapy for 7-10 days. 6. Establishing of a chlamydial diagnostic on a broad base.