Infante J R, Rayo J I, Serrano J, García L, Moreno M, Martínez A, Huertas J
Servicio de Medicina Nuclear, Complejo Hospitalario Universitario de Badajoz, Badajoz, España.
Servicio de Medicina Nuclear, Complejo Hospitalario Universitario de Badajoz, Badajoz, España.
Rev Esp Med Nucl Imagen Mol. 2017 May-Jun;36(3):146-151. doi: 10.1016/j.remn.2016.10.011. Epub 2016 Dec 10.
Chronic constipation is a common pathology in children. The aim of this paper was to show the usefulness of gastrointestinal transit scintigraphy in pediatric patients with chronic constipation, and the advantages with respect to other imaging techniques, despite our limited experience.
We evaluated 5 patients sent to our service with a diagnosis of chronic constipation refractory to treatment. We performed a complete study protocol, including liquid gastric emptying scintigraphy and small and large bowel transit times, using a single dose of In-DTPA. Following international guidelines regions of interest were defined in stomach, terminal ileum and in 6 regions of the large intestine.
All patients showed altered scintigraphy study, showing 4 of them normal radiological tests. Radioisotopic study changed diagnosis in 2 patients and in other 2 patients contributed to clarify it, since discordance between normal radiological tests and abnormal rectal biopsy. One of the patients showed concordance between each imaging modality. The results of the test changed the therapeutic management in 2 cases.
Our limited experience coincides with published data in which scintigraphy study turns out to be a reproducible and accurate method. It provides physiological, quantitative and useful information in the study of constipation, being the unique exploration that allows both global and regional gastrointestinal transit time determination.
慢性便秘是儿童常见的病症。本文旨在展示胃肠道通过闪烁扫描术在患有慢性便秘的儿科患者中的作用,以及相较于其他成像技术的优势,尽管我们的经验有限。
我们评估了5名因诊断为治疗难治性慢性便秘而转诊至我院的患者。我们使用单剂量的铟-二乙三胺五乙酸进行了完整的研究方案,包括液体胃排空闪烁扫描术以及小肠和大肠通过时间的检测。按照国际指南,在胃、回肠末端以及大肠的6个区域定义了感兴趣区。
所有患者的闪烁扫描术检查结果均有异常,其中4人的放射学检查结果正常。放射性同位素检查改变了2例患者的诊断,另外2例患者的诊断得以明确,因为放射学检查结果正常但直肠活检异常。1例患者的每种成像方式结果一致。该检查结果改变了2例患者的治疗管理。
我们有限的经验与已发表的数据相符,即闪烁扫描术检查是一种可重复且准确的方法。它在便秘研究中提供了生理、定量且有用的信息,是唯一能够测定整体及局部胃肠道通过时间的检查方法。