原子力显微镜压缩模拟脂质双层囊泡的弛豫。
Relaxation of a simulated lipid bilayer vesicle compressed by an atomic force microscope.
机构信息
Ottawa-Carleton Institute for Physics, University of Ottawa Campus, Ottawa, Ontario, Canada K1N 6N5.
出版信息
Phys Rev E. 2016 Nov;94(5-1):052408. doi: 10.1103/PhysRevE.94.052408. Epub 2016 Nov 15.
PMID:27967024
Abstract
Using coarse-grained molecular dynamics simulations, we study the relaxation of bilayer vesicles, uniaxially compressed by an atomic force microscope cantilever. The relaxation time exhibits a strong force dependence. Force-compression curves are very similar to recent experiments wherein giant unilamellar vesicles were compressed in a nearly identical manner.
摘要
我们使用粗粒化分子动力学模拟研究了由原子力显微镜悬臂压缩的双层囊泡的弛豫。弛豫时间表现出强烈的力依赖性。力-压缩曲线与最近的实验非常相似，在这些实验中，巨大的单层囊泡以几乎相同的方式被压缩。
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