对比增强组织谐波成像与相位反转谐波超声成像在肝细胞癌诊断中的应用比较

Contrast-Enhanced Tissue Harmonic Imaging versus Phase Inversion Harmonic Sonographic Imaging for the Delineation of Hepatocellular Carcinomas.

作者信息

Kono Masashi, Minami Yasunori, Iwanishi Mina, Minami Tomohiro, Chishina Hirokazu, Arizumi Tadaaki, Komeda Yoriaki, Sakurai Toshiharu, Takita Masahiro, Yada Norihisa, Ida Hiroshi, Hagiwara Satoru, Ueshima Kazuomi, Nishida Naoshi, Kudo Masatoshi

机构信息

Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osaka-Sayama, Japan.

出版信息

Oncology. 2017;92 Suppl 1:29-34. doi: 10.1159/000451014. Epub 2016 Dec 15.

DOI:10.1159/000451014

PMID:27974714

Abstract

OBJECTIVE

To compare contrast tissue harmonic imaging (THI) with low mechanical index (MI) and conventional contrast harmonic imaging (CHI) with respect to lesion visibility of hepatocellular carcinoma (HCC).

METHODS

One hundred and twenty-five patients (84 men and 41 women, age range 39-94 years, mean age 74 years) with 100 naïve HCCs and 30 lesions after radiofrequency ablation (RFA) for HCC were evaluated. One hundred and four patients had liver cirrhosis of Child-Pugh class A, and the remaining 21 had Child-Pugh class B cirrhosis. The lesion conspicuity and intratumoral echogenicity during the postvascular phase were compared using conventional CHI and contrast THI with low MI.

RESULTS

The MI values ranged from 0.20 to 0.30 on conventional CHI and from 0.30 to 0.35 on contrast THI. Regarding HCC lesion conspicuity, contrast THI with low MI was clearer in 79 lesions (60.8%), equal in 34 lesions (26.2%), and less clear in 17 lesions (13.1%) when compared with conventional CHI. The lesion conspicuity with contrast THI was significantly better than that with conventional CHI (p < 0.01). All of the postablative lesions were well delineated in patients who received RFA.

CONCLUSION

Low-MI contrast THI was superior to conventional CHI with respect to lesion visibility of HCCs and might offer good imaging for the guiding of RFA.

摘要

目的

比较低机械指数（MI）的对比组织谐波成像（THI）与传统对比谐波成像（CHI）在肝细胞癌（HCC）病变可视性方面的差异。

方法

对125例患者（84例男性和41例女性，年龄范围39 - 94岁，平均年龄74岁）进行评估，其中有100个初发HCC病变以及30个HCC射频消融（RFA）后的病变。104例患者为Child-Pugh A级肝硬化，其余21例为Child-Pugh B级肝硬化。使用传统CHI和低MI的对比THI比较血管后期病变的显影度和瘤内回声。

结果

传统CHI的MI值范围为0.20至0.30，对比THI的MI值范围为0.30至0.35。关于HCC病变的显影度，与传统CHI相比，低MI的对比THI在79个病变中更清晰（60.8%），在34个病变中相等（26.2%），在17个病变中较不清晰（13.1%）。对比THI的病变显影度明显优于传统CHI（p < 0.01）。所有接受RFA的患者的消融后病变均清晰显示。