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早产:首次生育时产妇年龄较小与肥胖有关吗?

Early Parturition: Is Young Maternal Age at First Birth Associated with Obesity?

作者信息

Patchen Loral, Leoutsakos Jeannie-Marie, Astone Nan M

机构信息

Obstetrics and Gynecology, MedStar Washington Hospital Center, Washington, District of Columbia.

School of Medicine, Johns Hopkins University, Baltimore, Maryland.

出版信息

J Pediatr Adolesc Gynecol. 2017 Oct;30(5):553-559. doi: 10.1016/j.jpag.2016.12.001. Epub 2016 Dec 20.

Abstract

STUDY OBJECTIVE

Examine the association of age at first birth with body mass index (BMI), and explore the role of young maternal age and subsequent obesity.

DESIGN, SETTING, PARTICIPANTS, AND INTERVENTIONS: This study analyzed data from the Panel Study of Income Dynamics, a nationally representative longitudinal study of US families. Analyses were conducted using a mixed effects longitudinal linear regression with a random intercept to examine the effect of aging, age at first birth, and minority status using nested data. Study criteria yielded a final sample of 146 women with 707 observations.

MAIN OUTCOME MEASURES

BMI.

RESULTS

Age at first birth exhibited a significant association with BMI. The association of age at first birth with BMI was greatest for women age 21 and younger. Overall, women who experienced their first birth at age 21 or younger had a BMI 5 units greater than women who delayed childbearing until at least age 30 (point estimate, 5.02; P = .02; 95% confidence interval, 0.65-9.40).

CONCLUSION

Young maternal age at first birth might be associated with increased BMI. Minority women also experience their first birth at younger ages compared with white women, suggesting possible linkages between the timing of reproductive events and obesity disparities.

摘要

研究目的

研究首次生育年龄与体重指数(BMI)之间的关联,并探讨年轻产妇年龄及随后肥胖的作用。

设计、背景、参与者及干预措施:本研究分析了收入动态面板研究的数据,这是一项对美国家庭具有全国代表性的纵向研究。采用混合效应纵向线性回归和随机截距,利用嵌套数据来分析衰老、首次生育年龄及少数族裔身份的影响。研究标准最终产生了一个由146名女性组成的样本,包含707条观察数据。

主要观察指标

BMI。

结果

首次生育年龄与BMI存在显著关联。首次生育年龄与BMI之间的关联在21岁及以下的女性中最为明显。总体而言,21岁及以下生育第一胎的女性的BMI比至少推迟到30岁生育的女性高5个单位(点估计值为5.02;P = 0.02;95%置信区间为0.65 - 9.40)。

结论

首次生育时产妇年龄较小可能与BMI升高有关。与白人女性相比,少数族裔女性首次生育的年龄也较小,这表明生育事件的时间与肥胖差异之间可能存在联系。

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