Mitruka Kiren, Volkmann Tyson, Pratt Robert H, Kammerer J Steve
Division of Tuberculosis Elimination, Centers for Disease Control and Prevention, Atlanta, Georgia.
Division of Tuberculosis Elimination, Centers for Disease Control and Prevention, Atlanta, Georgia.
Am J Prev Med. 2017 Apr;52(4):483-490. doi: 10.1016/j.amepre.2016.10.035. Epub 2016 Dec 21.
Treatment completion is the cornerstone of tuberculosis (TB) control strategy globally. Although the majority of reported TB cases in the U.S. have documented treatment completion, individuals diagnosed while incarcerated are less likely to have documentation of whether or not they completed treatment. This study assessed trends and correlates of no documented treatment completion among individuals incarcerated at diagnosis.
U.S. National TB Surveillance System (1999-2011) data on cases eligible for treatment completion were analyzed during 2014-2015. Treatment outcomes and trends in no documented completion were assessed by incarceration status. Multivariable logistic regression identified correlates of no documented completion among people incarcerated at diagnosis.
A lower proportion of individuals incarcerated at diagnosis had documented TB treatment completion than non-incarcerated individuals (75.6% vs 93.7%), and a higher proportion were lost to follow-up (10.7% vs 2.2%) or moved (9.4% vs 2.3%) during treatment (p<0.001). The 1999-2011 trend in no documented completion significantly increased among those incarcerated at diagnosis and declined among non-incarcerated individuals. Being foreign born was the strongest correlate of no documented completion among people incarcerated at diagnosis (AOR=2.86, 95% CI= 2.35, 3.49). Social risk factors for TB (e.g., homelessness, substance abuse), although common among incarcerated individuals, did not emerge as correlates of no documented completion.
People diagnosed with TB disease at U.S. correctional facilities, especially the foreign born, require enhanced strategies for documenting TB treatment completion. Strengthened collaboration between correctional and public health agencies could improve continuity of care among released inmates.
治疗完成是全球结核病控制策略的基石。尽管美国报告的大多数结核病病例都有治疗完成的记录,但在监禁期间被诊断出的个体完成治疗与否的记录较少。本研究评估了诊断时被监禁个体无治疗完成记录的趋势及其相关因素。
2014 - 2015年期间分析了美国国家结核病监测系统(1999 - 2011年)中符合治疗完成条件的病例数据。按监禁状态评估治疗结果和无记录完成治疗的趋势。多变量逻辑回归确定了诊断时被监禁人群无记录完成治疗的相关因素。
诊断时被监禁的个体中,有记录的结核病治疗完成比例低于未被监禁的个体(75.6%对93.7%),且在治疗期间失访(10.7%对2.2%)或转移(9.4%对2.3%)的比例更高(p<0.001)。1999 - 2011年期间,诊断时被监禁者无记录完成治疗的趋势显著上升,而未被监禁者则呈下降趋势。出生在国外是诊断时被监禁人群无记录完成治疗的最强相关因素(比值比=2.86,95%置信区间=2.35,3.49)。结核病的社会风险因素(如无家可归、药物滥用)虽然在被监禁个体中很常见,但并未成为无记录完成治疗的相关因素。
在美国惩教机构中被诊断患有结核病的人,尤其是出生在国外的人,需要加强记录结核病治疗完成情况的策略。惩教机构与公共卫生机构之间加强合作可以改善释放囚犯的连续护理。