耐多药革兰氏阴性菌定植患者的肺移植：一例报告
Lung Transplantation in a Multidrug-Resistant Gram-Negative -Colonized Patient: A Case Report.
作者信息
Huenges Katharina, Reinecke Alexander, Bewig Burkhard, Haneya Assad, Cremer Jochen
机构信息
Department of Cardiovascular Surgery, University of Schleswig-Holstein Campus Kiel, Kiel, Germany.
Department of Internal Medicine I, University of Schleswig Holstein Campus Kiel, Kiel, Germany.
出版信息
Thorac Cardiovasc Surg Rep. 2016 Dec;5(1):16-17. doi: 10.1055/s-0035-1569993. Epub 2015 Dec 16.
Abstract
Colonization or infection with various pathogens is frequently found in patients listed for lung transplantation. We describe a case of a 50-year-old woman with α-1-antitrypsin deficiency, which was listed for double-lung transplantation, with multidrug-resistant gram-negative (MRGN4-) skin colonization. Transplantation was successfully performed. Colistin (Polymyxine E) was administered intravenously and through inhalation in the first month. MRGN4- was still detectable in skin swabs without evidence of infection. After good recovery and clinical inapparence, the patient was discharged 2 months after transplantation.
摘要
在等待肺移植的患者中，经常发现其感染或定植有各种病原体。我们描述了一例50岁的α-1抗胰蛋白酶缺乏症女性患者，她在等待双肺移植时出现了耐多药革兰氏阴性菌（MRGN4-）皮肤定植。移植手术成功进行。在第一个月通过静脉和吸入方式给予了多粘菌素E（黏菌素）。在皮肤拭子中仍可检测到MRGN4-，但没有感染迹象。在恢复良好且临床症状消失后，患者在移植后2个月出院。
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