牛脂肪肝中蛋白激酶C活性降低。
Decreased protein kinase C activity in fatty liver from cattle.
作者信息
Katoh N, Kimura K
机构信息
Hokkaido Branch Laboratory, National Institute of Animal Health, Sapporo, Japan.
出版信息
Am J Vet Res. 1989 Sep;50(9):1489-92.
Protein kinase (PK) C activity in the liver of cattle with fatty liver syndrome was evaluated and compared with that in liver of healthy cattle. The PKC activities in cytosolic and particulate fractions were reduced in fatty livers, compared with those in livers from healthy cattle. The decrease of PKC activity was more distinct in cytosolic (P = 0.0016) than particulate (P = 0.069) fractions. Protein kinase activities other than PKC were not substantially changed. Seemingly, PKC was involved in the pathogenesis of fatty liver syndrome in cattle.
对患有脂肪肝综合征的牛肝脏中的蛋白激酶（PK）C活性进行了评估，并与健康牛肝脏中的该活性进行了比较。与健康牛的肝脏相比，脂肪肝中细胞溶质和微粒体部分的PKC活性降低。PKC活性的降低在细胞溶质部分（P = 0.0016）比微粒体部分（P = 0.069）更明显。除PKC外的其他蛋白激酶活性没有实质性变化。看来，PKC参与了牛脂肪肝综合征的发病机制。
Zotero 插件