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[在影响血管平滑肌的各种张力条件下对人手指动脉粘弹性特性的无创测定]

[Noninvasive determination of viscoelastic properties of human finger arteries under various tonus conditions affecting vascular smooth muscle].

作者信息

Bochmann R, Altmann O

机构信息

Zentrale Hochschulpoliklinik, Abteilung Pathophysiologie, Medizinische Akademie Carl Gustav Carus, Dresden, DDR.

出版信息

Biomed Biochim Acta. 1989;48(7):441-7.

PMID:2803281
Abstract

The amplitude of the volume pulse in relation to transmural pressure and the compliance as a viscoelastic property of the digital arteries were determined noninvasively in 9 male subjects (mean age 16 years). The amplitude of the volume pulse was measured impedance-plethysmographically and the amplitude of the pressure pulse sphygmomanometrically. The registration of the pulses was performed under different conditions (sitting-control), lying, 3-min forearm ischaemia, concentration-performance test, hyperventilation, 0.8 mg Nitrangin sublingual) to provoke different states of the vessel wall. The amplitude of the volume pulse under concentration-performance test (0.054 +/- 0.015 ml), hyperventilation (0.045 +/- 0.015 ml) and Nitrangin (0.142 +/- 0.034 ml) is significantly (p = 0.025) different from control (0.086 +/- 0.016 ml). The amplitude of the volume pulse and the compliance increase with decreasing transmural pressure.

摘要

在9名男性受试者(平均年龄16岁)中,以无创方式测定了与跨壁压力相关的容积脉搏幅度以及作为指动脉粘弹性特性的顺应性。容积脉搏幅度采用阻抗体积描记法测量,压力脉搏幅度采用血压计测量。在不同条件下(坐位-对照)、卧位、3分钟前臂缺血、注意力-操作测试、过度通气、舌下含服0.8毫克硝酸甘油)记录脉搏,以激发血管壁的不同状态。注意力-操作测试(0.054±0.015毫升)、过度通气(0.045±0.015毫升)和硝酸甘油(0.142±0.034毫升)时的容积脉搏幅度与对照(0.086±0.016毫升)相比有显著差异(p = 0.025)。容积脉搏幅度和顺应性随跨壁压力降低而增加。

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