口服巴氯芬戒断导致进行性肌无力和镇静，需入住重症监护病房。
Oral Baclofen Withdrawal Resulting in Progressive Weakness and Sedation Requiring Intensive Care Admission.
作者信息
Alvis Bret D, Sobey Christopher M
机构信息
Department of Anesthesiology, Critical Care Medicine, Vandertbilt University School of Medicine, Nashville, TN, USA.
Department of Anesthesiology, Division of Pain Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA.
出版信息
Neurohospitalist. 2017 Jan;7(1):39-40. doi: 10.1177/1941874416637404. Epub 2016 Mar 14.
Abstract
Baclofen is a common medication used as a muscle relaxant and antispasmodic. Baclofen-withdrawal syndrome has many symptoms such as sedation, somnolence, and weakness but can include psychological symptoms. We present a 62-year-old female whose oral baclofen was not continued at a skilled nursing facility after discharge following inpatient surgery that led to the development of altered mental status and respiratory insufficiency necessitating intensive care unit admission. Abrupt cessation of baclofen, no matter the mode of administration to the patient, can lead to baclofen-withdrawal syndrome.
摘要
巴氯芬是一种常用的肌肉松弛剂和抗痉挛药物。巴氯芬戒断综合征有许多症状，如镇静、嗜睡和虚弱，但也可能包括心理症状。我们报告一名62岁女性，她在住院手术后出院，在一家专业护理机构未继续服用口服巴氯芬，导致精神状态改变和呼吸功能不全，需要入住重症监护病房。无论给患者的给药方式如何，突然停用巴氯芬都可能导致巴氯芬戒断综合征。
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