• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

六水合尿酸氢钙的沉淀与溶解性

Precipitation and Solubility of Calcium Hydrogenurate Hexahydrate.

作者信息

Babić-Ivančić V, Füredi-Milhofer H, Brničević N, Marković M

机构信息

Rudjer Bošković Institute, Zagreb, Croatia.

Rudjer Bošković Institute and Faculty of Science, University of Zagreb, Zagreb, Croatia and American Dental Association Health Foundation, National Institute of Standards and Technology, Gaithersburg, MD 20899.

出版信息

J Res Natl Inst Stand Technol. 1992 May-Jun;97(3):365-372. doi: 10.6028/jres.097.015.

DOI:10.6028/jres.097.015
PMID:28053438
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4909170/
Abstract

Solid phases formed in the quaternary system: uric acid-calcium hydroxide -hydrochloric acid-water aged for 2 months at 310 K were studied to determine conditions for calcium hydrogenurate hexahydrate, Ca(CHNO) · 6HO precipitation. The precipitates were identified by chemical and thermogravimetric analyses, x-ray powder diffraction, infrared spectroscopy, light microscopy, and scanning electron microscopy. In the precipitation diagram the concentration region in which calcium hydrogenurate hexahydrate precipitated as a single solid phase was established. The solubility of calcium hydrogenurate hexahydrate was investigated in the pH range from 6.2 to 10.1 at different temperatures. The total soluble and ionic concentration of calcium (atomic absorption spectroscopy and Ca-selective electrode), total urate concentration (spectrophotometry), and pH were determined in equilibrated solutions. The data are presented in the form of tables and chemical potential diagrams. By using these data the thermodynamic solubility products of calcium hydrogenurate hexahydrate, = (Ca) · (CHNO), were determined: [Formula: see text]The formation of calcium hydrogenurate hexahydrate crystals in urinary tract of patients with pathologically high concentrations of calcium and urates (hypercalciuria and hyperuricosiuria) is possible.

摘要

对在310 K下老化2个月的四元体系：尿酸 - 氢氧化钙 - 盐酸 - 水所形成的固相进行了研究，以确定六水合尿酸氢钙Ca(CHNO)·6HO沉淀的条件。通过化学分析、热重分析、X射线粉末衍射、红外光谱、光学显微镜和扫描电子显微镜对沉淀物进行了鉴定。在沉淀图中确定了六水合尿酸氢钙作为单一固相沉淀的浓度区域。研究了六水合尿酸氢钙在不同温度下pH值为6.2至10.1范围内的溶解度。在平衡溶液中测定了钙的总可溶性和离子浓度（原子吸收光谱法和钙选择性电极）、尿酸盐总浓度（分光光度法）以及pH值。数据以表格和化学势图的形式呈现。利用这些数据确定了六水合尿酸氢钙的热力学溶度积 = (Ca)·(CHNO)：[公式：见正文]在钙和尿酸盐浓度病理性升高（高钙尿症和高尿酸尿症）的患者尿路中，有可能形成六水合尿酸氢钙晶体。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3af8/4909170/d78c98614a4c/jresv97n3p365_a1bf4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3af8/4909170/b3e41d4f1385/jresv97n3p365_a1bf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3af8/4909170/4a039eb147a4/jresv97n3p365_a1bf2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3af8/4909170/cc68954fa075/jresv97n3p365_a1bf3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3af8/4909170/d78c98614a4c/jresv97n3p365_a1bf4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3af8/4909170/b3e41d4f1385/jresv97n3p365_a1bf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3af8/4909170/4a039eb147a4/jresv97n3p365_a1bf2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3af8/4909170/cc68954fa075/jresv97n3p365_a1bf3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3af8/4909170/d78c98614a4c/jresv97n3p365_a1bf4.jpg

相似文献

1
Precipitation and Solubility of Calcium Hydrogenurate Hexahydrate.六水合尿酸氢钙的沉淀与溶解性
J Res Natl Inst Stand Technol. 1992 May-Jun;97(3):365-372. doi: 10.6028/jres.097.015.
2
Influence of pH, temperature and common ion on magnesium hydrogenurate octahydrate solubility.pH值、温度和共同离子对八水合氢尿酸镁溶解度的影响。
Coll Antropol. 2010 Mar;34 Suppl 1:259-66.
3
In vitro assessment of the formation of ceftriaxone-calcium precipitates in human plasma.在人血浆中评估头孢曲松钙沉淀物形成的体外研究。
J Pharm Sci. 2011 Jun;100(6):2300-10. doi: 10.1002/jps.22466. Epub 2011 Jan 19.
4
Calcium hydroxy palmitate: possible precursor phase in calcium precipitation by palmitate.钙羟棕榈酸酯：棕榈酸钙沉淀的可能前体相。
Food Chem. 2013 Jun 15;138(4):2415-20. doi: 10.1016/j.foodchem.2012.12.012. Epub 2012 Dec 21.
5
The solubility of calcium and phosphate in two specialty amino acid solutions.钙和磷酸盐在两种特殊氨基酸溶液中的溶解度。
JPEN J Parenter Enteral Nutr. 1996 Jan-Feb;20(1):63-6. doi: 10.1177/014860719602000163.
6
Bioactivity of calcium aluminate endodontic cement.钙铝酸盐根管封闭剂的生物活性。
J Endod. 2013 Jun;39(6):774-8. doi: 10.1016/j.joen.2013.01.013. Epub 2013 Mar 21.
7
Solubility of hydroxyapatite by solid titration at pH 3-4.在pH值为3 - 4时通过固体滴定法测定羟基磷灰石的溶解度。
Arch Oral Biol. 2007 Jul;52(7):618-24. doi: 10.1016/j.archoralbio.2006.12.007. Epub 2007 Jan 22.
8
Simultaneous removal of phosphorus and potassium from synthetic urine through the precipitation of magnesium potassium phosphate hexahydrate.通过六水合磷酸镁钾的沉淀从合成尿中同时去除磷和钾。
Chemosphere. 2011 Jun;84(2):207-12. doi: 10.1016/j.chemosphere.2011.04.057. Epub 2011 May 18.
9
Formation of crystalline Zn-Al layered double hydroxide precipitates on γ-alumina: the role of mineral dissolution.晶态 Zn-Al 层状双氢氧化物在 γ-氧化铝上的形成：矿物溶解的作用。
Environ Sci Technol. 2012 Nov 6;46(21):11670-7. doi: 10.1021/es3018094. Epub 2012 Oct 25.
10
Urates in uric acid renal calculi.
Int J Urol. 2009 Mar;16(3):318-21; discussion 322. doi: 10.1111/j.1442-2042.2008.02244.x. Epub 2009 Jan 20.

本文引用的文献

1
Observations on the analysis of ten thousand urinary calculi.一万例尿结石分析观察报告
J Urol. 1962 Oct;88:545-62. doi: 10.1016/S0022-5347(17)64842-0.
2
Epitaxial considerations in urinary stone formation. I. The urate-oxalate-phosphate system.尿路结石形成中的外延因素。I.尿酸盐 - 草酸盐 - 磷酸盐系统。
Invest Urol. 1980 Sep;18(2):178-84.
3
[Etiology of uric acid lithiasis. I. Solubility of uric acid and sodium urate in buffer solution].[尿酸结石的病因。I. 尿酸和尿酸钠在缓冲溶液中的溶解度]
Rev Fr Etud Clin Biol. 1966 Jan;11(1):40-8.
4
Inhibition of monosodium urate needle crystal growth.尿酸钠针状晶体生长的抑制
Arthritis Rheum. 1965 Dec;8(6):1123-33. doi: 10.1002/art.1780080611.
5
The acute attack of gouty arthritis.痛风性关节炎急性发作。
Arthritis Rheum. 1965 Oct;8(5):714-25. doi: 10.1002/art.1780080431.
6
Uric acid, uric acid dihydrate, and urates in urinary calculi, ancient and modern.古今尿石症中的尿酸、二水合尿酸及尿酸盐
Science. 1966 Jun 10;152(3728):1511-2. doi: 10.1126/science.152.3728.1511.
7
Solubility of uric acid and monosodium urate.尿酸和尿酸钠的溶解度。
Med Biol Eng. 1972 Jul;10(4):522-31. doi: 10.1007/BF02474201.
8
Human stones.人体结石
Science. 1968 Mar 15;159(3820):1199-207. doi: 10.1126/science.159.3820.1199.
9
[Thermoanalytical examination of kidney calculi. I. Calculi components with purine structure].[肾结石的热分析检查。I. 具有嘌呤结构的结石成分]
Z Urol Nephrol. 1967 Jun;60(6):361-8.
10
The epitaxially induced crystal growth of calcium oxalate by crystalline uric acid.
Invest Urol. 1976 Sep;14(2):115-9.