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[不同病理类型炎性肌纤维母细胞瘤的CT表现]

[CT findings of inflammatory myofibroblastic tumor of different pathological types].

作者信息

Zhao X T, Yue S W, Cheng Q, Liu P, Chang L Y, Zhao X X, Liang P

机构信息

First Affiliated Hospital of Zhengzhou University, Zhengzhou 450000, China.

出版信息

Zhonghua Yi Xue Za Zhi. 2017 Jan 3;97(1):43-46. doi: 10.3760/cma.j.issn.0376-2491.2017.01.011.

Abstract

To explore the computed tomography(CT) features of inflammatory myofibroblastic tumor(IMT) in different pathological types, and improve the diagnostic level of this disease. The CT features of 29 cases pathologically confirmed IMTs were retrospectively reviewed along with a literature review to analyze the CT features and pathological correlations, and three kinds of pathological classification of IMT in patients with gender , shape, boundary and location were respectively analyzed by - test. The age ranges from 2 to 78 years.There were 7 cases of mucinous blood vessel type and 13 cases of spindle cell type and 9 cases of fiber type.Immunohistochemically, Vimentin (22/29) and SMA (28/29) were positive in all the cases, ALK (4/29) and CD-67(6/29) were partly positive expression, other markers such as S-100 were negative expression.The - test showed that there were statistically differences in the gender of the patients. The CT and clinical features differ according to pathological types of IMT. Its final diagnosis still needs to be combined with pathology and immunohistochemistry result. In all, CT has a role in assessing the extension of IMT and especially about the relationship with adjacent organs which can effectively direct the establishment of clinical treating scheme.

摘要

探讨不同病理类型炎性肌纤维母细胞瘤(IMT)的计算机断层扫描(CT)特征,提高该病的诊断水平。回顾性分析29例经病理证实的IMT的CT特征,并结合文献分析CT特征与病理的相关性,采用t检验分别分析IMT三种病理分类在患者性别、形态、边界及位置方面的差异。年龄范围为2至78岁。黏液血管型7例,梭形细胞型13例,纤维型9例。免疫组化结果显示,所有病例中波形蛋白(22/29)和平滑肌肌动蛋白(SMA,28/29)均呈阳性,间变性淋巴瘤激酶(ALK,4/29)和CD-67(6/29)呈部分阳性表达,其他标志物如S-100呈阴性表达。t检验显示患者性别存在统计学差异。IMT的CT表现及临床特征因病理类型而异。其最终诊断仍需结合病理及免疫组化结果。总体而言,CT在评估IMT的范围,尤其是与相邻器官的关系方面具有作用,可有效指导临床治疗方案的制定。

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