食物成瘾与药物成瘾:异同之处

Food and drug addictions: Similarities and differences.

作者信息

Rogers Peter J

机构信息

Nutrition and Behaviour Unit, School of Experimental Psychology, University of Bristol, Bristol, UK.

出版信息

Pharmacol Biochem Behav. 2017 Feb;153:182-190. doi: 10.1016/j.pbb.2017.01.001. Epub 2017 Jan 4.

Abstract

This review examines the merits of 'food addiction' as an explanation of excessive eating (i.e., eating in excess of what is required to maintain a healthy body weight). It describes various apparent similarities in appetites for foods and drugs. For example, conditioned environmental cues can arouse food and drug-seeking behaviour, 'craving' is an experience reported to precede eating and drug taking, 'bingeing' is associated with both eating and drug use, and conditioned and unconditioned tolerance occurs to food and drug ingestion. This is to be expected, as addictive drugs tap into the same processes and systems that evolved to motivate and control adaptive behaviours, including eating. The evidence, however, shows that drugs of abuse have more potent effects than foods, particularly in respect of their neuroadaptive effects that make them 'wanted.' While binge eating has been conceptualised as form of addictive behaviour, it is not a major cause of excessive eating, because binge eating has a far lower prevalence than obesity. Rather, it is proposed that obesity results from recurrent overconsumption of energy dense foods. Such foods are, relatedly, both attractive and (calorie for calorie) weakly satiating. Limiting their availability could partially decrease excessive eating and consequently decrease obesity. Arguably, persuading policy makers that these foods are addictive could support such action. However, blaming excessive eating on food addiction could be counterproductive, because it risks trivialising serious addictions, and because the attribution of excessive eating to food addiction implies an inability to control one's eating. Therefore, attributing everyday excessive eating to food addiction may neither explain nor significantly help reduce this problem.

摘要

本综述探讨了“食物成瘾”作为过度进食(即进食量超过维持健康体重所需量)一种解释的合理性。它描述了对食物和药物的食欲方面的各种明显相似之处。例如,条件性环境线索可引发对食物和药物的寻求行为,“渴望”被报告为进食和服药之前的一种体验,“暴饮暴食”与进食和药物使用都有关,并且对食物和药物摄入会出现条件性和非条件性耐受。这是可以预料的,因为成瘾性药物利用了与进化来激励和控制包括进食在内的适应性行为相同的过程和系统。然而,证据表明,滥用药物的影响比食物更强,特别是在使其“被渴望”的神经适应性影响方面。虽然暴饮暴食已被概念化为成瘾行为的一种形式,但它并非过度进食的主要原因,因为暴饮暴食的患病率远低于肥胖症。相反,有人提出肥胖是由于反复过度食用能量密集型食物所致。与此相关的是,这类食物既具有吸引力,而且(按卡路里计算)饱腹感较弱。限制其供应可能会部分减少过度进食,从而降低肥胖率。可以说,说服政策制定者相信这些食物具有成瘾性可能会支持此类行动。然而,将过度进食归咎于食物成瘾可能会适得其反,因为这有将严重成瘾问题 trivialising 的风险,并且因为将过度进食归因于食物成瘾意味着无法控制自己的饮食。因此,将日常的过度进食归因于食物成瘾既无法解释也无助于显著减少这一问题。

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