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[介质中的钠离子对输尿管中峰电位活动产生的作用]

[The role of sodium ions of the medium on the generation of spike activity in the ureter].

作者信息

Kazarian K V, Oganesian A S, Tiraian A S, Akopian R R, Martirosov S M

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1989 Jun;75(6):845-50.

PMID:2806649
Abstract

In sodium-free Krebs solution ureter cells are able to generate action potentials. Logarithm of time, during which spikes are generated, is in proportion to the concentration of calcium ions in the surrounding medium in interval from 2.5 to 15 mmol/l. The addition of 20 mmol/l Na+ ions into the external solution is able to reestablish prolonged electrical activity of ureter. In sodium-free solution it is possible the reestablishment of short duration activity which depends on K+ ions concentration in surroundings. It is supposed that intracellular concentration of calcium ions in ureter may be regulated with the help of Na+/Ca++ exchange mechanism.

摘要

在无钠的 Krebs 溶液中,输尿管细胞能够产生动作电位。产生尖峰的时间对数与周围介质中钙离子浓度在 2.5 至 15 mmol/l 的区间内成比例。向外部溶液中添加 20 mmol/l 的 Na+离子能够恢复输尿管的长时间电活动。在无钠溶液中,有可能恢复取决于周围环境中 K+离子浓度的短时间活动。据推测,输尿管中钙离子的细胞内浓度可能借助 Na+/Ca++交换机制进行调节。

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