Pal Bipin Chandra, Modi Pranjal R, Qadri Syed Javid Farooq, Modi Jayesh, Kumar Suresh, Nagarajan Ramya, Safee Yusuf
Department of Urology and Transplantation Surgery, Institute of Kidney Diseases and Research Center and Dr. H.L. Trivedi Institute of Transplantation Sciences, Civil Hospital Campus, Ahmedabad, Gujarat, India.
J Indian Assoc Pediatr Surg. 2017 Jan-Mar;22(1):23-28. doi: 10.4103/0971-9261.194616.
Urethroplasty in pediatric patients is a challenging task. In this study, we have tried to assess the complexity and evaluate the outcome of progressive perineal anastomotic urethroplasty in prepubertal children.
Retrospective data of all the prepubertal children who underwent progressive perineal urethroplasty between March 2009 and April 2014 were analyzed. Patients were evaluated with history, examination, essential laboratory investigations, retrograde urethrogram, and voiding cystourethrogram. Before subjecting the patients for definitive surgery, antegrade and retrograde endoscopic assessment was done. The surgery was performed by the transperineal route with the help of ×2.5 magnification. Patients were followed up with uroflowmetry for every 3 months in the 1 year and for every 6 months in the subsequent years.
Mean age of the patients was 7.3 (range 5-11) years. Mean urethral distraction defect was 1.7 (range 1-2.5) cm. All the patients were successfully managed by the perineal approach. Crural separation was performed in all the patients while additional inferior pubectomy was required in six patients. Mean operating time was 298 (range 180-400) min. Mean blood loss was 174 (range 100-500) ml. One patient had the left calf hematoma in the immediate postoperative period. Seven out of nine (77.7%) patients had successful urethroplasty. Two patients had failed urethroplasty who were successfully managed by redo-urethroplasty. Transient incontinence was observed in one patient. Erectile function could not be assessed in these patients.
This study shows the feasibility of progressive perineal urethroplasty by the perineal route in prepubertal children. An endoscopic assessment should be performed before the definitive surgery. Use of loupe helps in performing better anastomosis and hence yielding a better result.
小儿尿道成形术是一项具有挑战性的任务。在本研究中,我们试图评估青春期前儿童进行渐进性会阴吻合尿道成形术的复杂性并评估其结果。
分析2009年3月至2014年4月间接受渐进性会阴尿道成形术的所有青春期前儿童的回顾性数据。通过病史、检查、必要的实验室检查、逆行尿道造影和排尿性膀胱尿道造影对患者进行评估。在对患者进行确定性手术之前,进行顺行和逆行内镜评估。手术通过会阴途径在2.5倍放大倍数的帮助下进行。患者在术后1年内每3个月进行一次尿流率随访,此后每6个月进行一次。
患者的平均年龄为7.3岁(范围5 - 11岁)。平均尿道牵引缺损为1.7厘米(范围1 - 2.5厘米)。所有患者均通过会阴途径成功治疗。所有患者均进行了阴茎脚分离,6例患者需要额外进行耻骨下切除术。平均手术时间为298分钟(范围180 - 400分钟)。平均失血量为174毫升(范围100 - 500毫升)。1例患者在术后即刻出现左小腿血肿。9例患者中有7例(77.7%)尿道成形术成功。2例尿道成形术失败的患者通过再次尿道成形术成功治疗。1例患者出现短暂性尿失禁。这些患者的勃起功能无法评估。
本研究表明,青春期前儿童通过会阴途径进行渐进性会阴尿道成形术是可行的。在确定性手术前应进行内镜评估。使用放大镜有助于进行更好的吻合,从而获得更好的结果。