Nelson Sarah, Cunningham Natoshia, Peugh James, Jagpal Anjana, Arnold Leslie M, Lynch-Jordan Anne, Kashikar-Zuck Susmita
Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts.
Cincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, Ohio.
Arthritis Care Res (Hoboken). 2017 Nov;69(11):1636-1643. doi: 10.1002/acr.23192. Epub 2017 Sep 21.
To examine the differential presentation(s) of psychological and health-related outcomes in young adults with juvenile-onset fibromyalgia (FM) with and without a history of trauma, compared to healthy controls.
In total, 110 participants (86 with juvenile-onset FM and 24 healthy controls, with a mean age of 23.4 years) completed a structured clinical interview to assess for trauma and psychological comorbidities, as well as self-report questionnaires on pain, physical functioning, and health care utilization.
Of the juvenile-onset FM participants, 37% (n = 32) reported a history of trauma. Three group comparisons (i.e., juvenile-onset FM with trauma versus juvenile-onset FM with no trauma versus healthy controls) revealed that juvenile-onset FM participants significantly differed from healthy controls on all psychological and health-related outcomes. Further, although juvenile-onset FM participants with and without a history of trauma did not significantly differ on pain and physical functioning, juvenile-onset FM participants with a history of trauma were significantly more likely to have psychological comorbidities.
This is the first controlled study to examine the differential outcomes between juvenile-onset FM participants with and without a history of trauma. Group comparisons between juvenile-onset FM participants and healthy controls were consistent with previous research. Further, our findings indicate that juvenile-onset FM participants with a history of trauma experience greater psychological, but not physical, impairment than juvenile-onset FM participants without a history of trauma.
与健康对照组相比,研究有或无创伤史的青少年起病型纤维肌痛(FM)青年成人在心理和健康相关结局方面的差异表现。
总共110名参与者(86名青少年起病型FM患者和24名健康对照者,平均年龄23.4岁)完成了一项结构化临床访谈,以评估创伤和心理共病情况,以及关于疼痛、身体功能和医疗保健利用的自我报告问卷。
在青少年起病型FM参与者中,37%(n = 32)报告有创伤史。三组比较(即有创伤的青少年起病型FM患者与无创伤的青少年起病型FM患者与健康对照者)显示,青少年起病型FM参与者在所有心理和健康相关结局方面与健康对照者有显著差异。此外,尽管有和无创伤史的青少年起病型FM参与者在疼痛和身体功能方面没有显著差异,但有创伤史的青少年起病型FM参与者更有可能患有心理共病。
这是第一项对照研究,旨在检查有或无创伤史的青少年起病型FM参与者之间的不同结局。青少年起病型FM参与者与健康对照者之间的组间比较与先前的研究一致。此外,我们的研究结果表明,有创伤史的青少年起病型FM参与者比无创伤史的青少年起病型FM参与者经历更大的心理损害,但身体损害并非如此。