Jang Seung-Ho, Ryu Han-Seung, Choi Suck-Chei, Lee Hye-Jin, Lee Sang-Yeol
a Department of Psychiatry, School of Medicine & Hospital , Wonkwang University , Iksan , Republic of Korea.
b Division of Gastroenterology, Department of Internal Medicine, School of Medicine , Wonkwang University , Iksan , Republic of Korea.
Women Health. 2018 Jan;58(1):112-127. doi: 10.1080/03630242.2017.1282394. Epub 2017 Jan 17.
This study investigated the psychological factors related to the overlap syndrome, i.e., multiple gastrointestinal conditions that are part of functional gastrointestinal disorders (FGIDs) in the same individual and potentially related to quality of life (QOL) among women aged 45-60 years (n = 627) in South Korea. The study was undertaken between July 2014 and March 2015. Depressive and anxiety symptoms were ascertained using the Center for Epidemiologic Studies Depression scale (CES-D) and the Beck Anxiety Inventory (BAI), respectively. Negative cognition and the cognitive triad were identified using the Automatic Thoughts Questionnaire-Negative (ATQ-N) and the Cognitive Triad Inventory (CTI), respectively. Resilience and QOL were assessed using the Connor-Davidson Resilience Scale (CD-RISC) and World Health Organization Quality of Life scale abbreviated version (WHOQOL-BREF). Women with the overlap syndrome had the highest CES-D (mean = 16.66 ± 11.79, p < .001), BAI (mean = 17.46 ± 12.67, p < .001), and ATQ-N scores (mean = 53.61 ± 20.88, p < .001), followed by women with gastrointestinal disorders but without the overlap syndrome and healthy controls. Healthy controls had the highest WHOQOL-BREF score (mean = 77.69 ± 12.53, p < .001). After stepwise selection, the final model explained 61.8 percent of the variance in QOL. Thus, depressive symptoms, anxiety, negative cognition, cognitive triad, and resilience were significantly related to QOL in women with the overlap syndrome.
本研究调查了与重叠综合征相关的心理因素，重叠综合征即同一个体中属于功能性胃肠疾病（FGIDs）的多种胃肠病症，且可能与韩国45至60岁女性（n = 627）的生活质量（QOL）相关。该研究于2014年7月至2015年3月期间进行。分别使用流行病学研究中心抑郁量表（CES-D）和贝克焦虑量表（BAI）确定抑郁和焦虑症状。分别使用消极自动思维问卷（ATQ-N）和认知三联征量表（CTI）识别消极认知和认知三联征。使用康纳-戴维森心理韧性量表（CD-RISC）和世界卫生组织生活质量简表（WHOQOL-BREF）评估心理韧性和生活质量。患有重叠综合征的女性CES-D得分最高（均值 = 16.66 ± 11.79，p <.001）、BAI得分最高（均值 = 17.46 ± 12.67，p <.001）以及ATQ-N得分最高（均值 = 53.61 ± 20.88，p <.001），其次是患有胃肠疾病但无重叠综合征的女性和健康对照组。健康对照组的WHOQOL-BREF得分最高（均值 = 77.69 ± 12.53，p <.001）。经过逐步选择，最终模型解释了生活质量变异的61.8%。因此，抑郁症状、焦虑、消极认知、认知三联征和心理韧性与患有重叠综合征的女性的生活质量显著相关。
