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股腘段变形的体内定量分析:经皮腔内血管成形术与镍钛合金支架置入术的比较

In Vivo Quantification of the Deformations of the Femoropopliteal Segment: Percutaneous Transluminal Angioplasty vs Nitinol Stent Placement.

作者信息

Gökgöl Can, Schumann Steffen, Diehm Nicolas, Zheng Guoyan, Büchler Philippe

机构信息

1 Institute for Surgical Technology & Biomechanics, University of Bern, Switzerland.

2 Clinical and Interventional Angiology, Vascular Institute Central Switzerland, Aarau, Switzerland.

出版信息

J Endovasc Ther. 2017 Feb;24(1):27-34. doi: 10.1177/1526602816677530. Epub 2016 Nov 15.

Abstract

PURPOSE

To quantify the deformations of the femoropopliteal (FP) segment in patients undergoing endovascular revascularization and to compare the posttreatment deformations caused by primary nitinol stent implantation to those produced by percutaneous transluminal angioplasty (PTA).

METHODS

Thirty-five patients (mean age 69±10 years; 20 men) scheduled for endovascular therapy were recruited for the study. During endovascular interventions, angiographic images were acquired with the legs straight and with a hip/knee flexion of 20°/70°. Image acquisition was performed before PTA for all patients, after PTA in 17 patients receiving this treatment only, and after primary stent implantation in the remaining 18 patients. A semiautomatic approach was used to reconstruct the 3-dimensional patient-specific artery models from 2-dimensional radiographs. Axial shortening and curvature changes in the arteries in vivo were calculated for the calcified, dilated, and stented regions, as well as the regions that were distal and proximal to the diseased and treated segments.

RESULTS

Leg flexion resulted in shortening of the artery in all investigated FP segments. The dilated arteries exhibited greater shortening compared with their stented counterparts (post-PTA 7.6%±4.9%, poststent 3.2%±2.9%; p=0.004). Leg flexion also led to an increase in the curvatures of all the sections of the FP segment. While stented arteries had significantly higher curvature values than PTA within the regions proximal to the treated sections, the choice of the treatment method did not affect the curvature of the other segments. Despite this, 40% of the stented arteries exhibited kinking during leg flexion.

CONCLUSION

The choice of the treatment method affects the postinterventional axial deformations of the FP segment but does not influence the curvature behavior. While PTA results in a more flexible artery, stents restrict the arteries' shortening capabilities. Depending on the anatomical position of the stents, this axial stiffening of the arteries may lead to chronic kinking, which may cause occlusions and, consequently, affect the long-term success of the procedure.

摘要

目的

量化接受血管内血运重建治疗患者的股腘(FP)段变形情况,并比较初次镍钛诺支架植入与经皮腔内血管成形术(PTA)所引起的治疗后变形。

方法

招募35例计划接受血管内治疗的患者(平均年龄69±10岁;20例男性)进行研究。在血管内干预过程中,在腿部伸直以及髋/膝关节屈曲20°/70°时采集血管造影图像。所有患者在PTA前进行图像采集,仅接受该治疗的17例患者在PTA后进行图像采集,其余18例患者在初次支架植入后进行图像采集。采用半自动方法从二维X线片重建三维患者特异性动脉模型。计算体内钙化、扩张和置入支架区域以及病变和治疗段远端和近端区域动脉的轴向缩短和曲率变化。

结果

腿部屈曲导致所有研究的FP段动脉缩短。与置入支架的动脉相比,扩张的动脉缩短更明显(PTA后7.6%±4.9%,置入支架后3.2%±2.9%;p = 0.004)。腿部屈曲还导致FP段所有节段的曲率增加。虽然在治疗段近端区域,置入支架的动脉曲率值显著高于PTA,但治疗方法的选择并未影响其他节段的曲率。尽管如此,40%的置入支架的动脉在腿部屈曲时出现扭结。

结论

治疗方法的选择影响FP段介入后的轴向变形,但不影响曲率变化。虽然PTA使动脉更具柔韧性,但支架限制了动脉的缩短能力。根据支架的解剖位置,动脉的这种轴向僵硬可能导致慢性扭结,进而可能导致闭塞,从而影响手术的长期成功率。

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