Estêvão Roberto, Santos Tiago, Ferreira Ana, Machado Anabela, Fernandes João, Monteiro Eurico
Serviço de Otorrinolaringologia. Centro Hospitalar do Alto Ave. Guimarães. Portugal.
Serviço de Otorrinolaringologia. Centro Hospitalar Entre Douro e Vouga. Aveiro. Portugal.
Acta Med Port. 2016 Oct;29(10):597-604. doi: 10.20344/amp.7003. Epub 2016 Oct 31.
In Portugal there are still no epidemiological and demographic studies conducted in patients with of the head and neck tumors. The objectives of this analysis are to describe the epidemiological and demographics of patients with malignant tumors of the head and neck referred to an Ear, Nose and Throat department of an oncology center in the North of Portugal and also assess the impact of these characteristics on survival.
Retrospective study of patients referred between January 2011 and December 2013 to the Ear, Nose and Throat Department of an oncology center (Instituto Português de Oncologia do Porto),. Five hundred sixty six patients were included. The analyzed variables were the anatomical location of the tumor, staging, gender and age of patients, the district of origin, the alcohol and tobacco consumption, educational level, occupation, marital status and family structure.
The 566 patients studied (498 men and 68 women) presented a mean age of 58.1 ± 12.2 years. The majority (80.5%) were referenced in advanced stage of disease (III and IV). Seventy eight per cent of patients had moderate or excessive alcohol consumption and 69% were smokers. The vast majority of patients (82.3%) had only basic education. Patients with tumors of the hypopharynx and excessive drinking habits were referenced in more advanced stages and had a poorer survival (p < 0.001). Married patients were referred at earlier stages (p = 0.020) and patients without family support had poorer survival (p = 0.030).
Epidemiological data are in agreement with the international literature. The high rate of patients referred with advanced stage of disease can be attributed to the patient´s delay in seeking medical care or by factors inherent to the referral system. Surveillance and family support play a key role in early referral and survival of these patients.
This study features a population profile that can benefit from a higher degree of surveillance, awareness campaigns and/ or screenings. Some of the variables can significantly influence the tumor stage and survival.
在葡萄牙,尚未对头颈部肿瘤患者进行流行病学和人口统计学研究。本分析的目的是描述转诊至葡萄牙北部一家肿瘤中心耳鼻喉科的头颈部恶性肿瘤患者的流行病学和人口统计学特征,并评估这些特征对生存的影响。
对2011年1月至2013年12月转诊至一家肿瘤中心(波尔图葡萄牙肿瘤研究所)耳鼻喉科的患者进行回顾性研究。纳入了566例患者。分析的变量包括肿瘤的解剖位置、分期、患者的性别和年龄、原籍地区、酒精和烟草消费情况、教育水平、职业、婚姻状况和家庭结构。
所研究的566例患者(498例男性和68例女性)的平均年龄为58.1±12.2岁。大多数患者(80.5%)在疾病晚期(III期和IV期)被转诊。78%的患者有中度或过量饮酒,69%为吸烟者。绝大多数患者(82.3%)只有基础教育水平。下咽肿瘤患者且有过量饮酒习惯的患者在更晚期被转诊,且生存较差(p<0.001)。已婚患者在较早阶段被转诊(p=0.020),没有家庭支持的患者生存较差(p=0.030)。
流行病学数据与国际文献一致。疾病晚期转诊患者比例高可归因于患者就医延迟或转诊系统的固有因素。监测和家庭支持在这些患者的早期转诊和生存中起关键作用。
本研究呈现了一个可从更高程度的监测、宣传活动和/或筛查中受益的人群特征。一些变量可显著影响肿瘤分期和生存。