Staley James T, Fuerst John A
Department of Microbiology and Astrobiology Program, University of Washington, Seattle 98195, USA.
School of Chemistry and Molecular Biosciences, University of Queensland, St. Lucia, Queensland 4072, Australia.
Res Microbiol. 2017 Jun;168(5):395-412. doi: 10.1016/j.resmic.2017.01.001. Epub 2017 Jan 19.
The nuclear compartment commonality (NuCom) hypothesis posits a complex last common ancestor (LUCA) with membranous compartments including a nuclear membrane. Such a LUCA then evolved to produce two nucleated lineages of the tree of life: the Planctomycetes-Verrucomicrobia-Chlamydia superphylum (PVC) within the Bacteria, and the Eukarya. We propose that a group of ancient essential protokaryotic signature proteins (PSPs) originating in LUCA were incorporated into ancestors of PVC Bacteria and Eukarya. Tubulins, ubiquitin system enzymes and sterol-synthesizing enzymes are consistent with early origins of these features shared between the PVC superphylum and Eukarya.
核区室共性（NuCom）假说假定存在一个具有膜性区室（包括核膜）的复杂的最后共同祖先（LUCA）。这样一个LUCA随后进化产生了生命树的两个有核谱系：细菌中的浮霉菌-疣微菌-衣原体超门（PVC）和真核生物。我们提出，一组起源于LUCA的古老的必需原核生物标志性蛋白（PSP）被纳入了PVC细菌和真核生物的祖先中。微管蛋白、泛素系统酶和固醇合成酶与PVC超门和真核生物之间共享的这些特征的早期起源是一致的。
