Cisse M F, Sow H D, Ouangre A R, Gaye A, Sow A I, Samb A, Fall M
Laboratoire de Bactériologie-Virologie, Faculté de Médecine et de Pharmacie, Dakar, Sénégal.
Med Trop (Mars). 1989 Jul-Sep;49(3):265-9.
Purulent bacterial meningitides are a very important pediatric problem in tropical areas. From February 1983 to February 1988, 409 cerebrospinal fluid samples from children with purulent meningitides, aged under 15 years, admitted to the Pediatric Hospital Albert Royer, Dakar, were examined for the presence of bacterial agents. In 222 (54.2%) samples, one bacterial agent or soluble antigens were detected. Among these, 3 bacterial agents were most frequently identified: 94 (42.3%) Haemophilus influenzae, 71 (31.9%) Streptococcus pneumoniae and 25 (11.2%) Neisseria meningitidis. The increase in bacterial meningitides observed during cool and dry seasons was essentially due to Haemophilus influenzae and Streptococcus pneumoniae. The bacterial strains were found to be susceptible to antibiotics usually administered. However, almost 22% of Haemophilus influenzae strains were resistant to ampicillin or chloramphenicol. A high mortality (33%) was observed, especially with Streptococcus pneumoniae. The purulent bacterial meningitides are a most important pediatric problem in tropical areas.
化脓性细菌性脑膜炎在热带地区是一个非常重要的儿科问题。1983年2月至1988年2月,对达喀尔阿尔贝·罗耶儿童医院收治的15岁以下患有化脓性脑膜炎的儿童的409份脑脊液样本进行了细菌病原体检测。在222份(54.2%)样本中,检测到一种细菌病原体或可溶性抗原。其中,最常鉴定出3种细菌病原体:94份(42.3%)流感嗜血杆菌、71份(31.9%)肺炎链球菌和25份(11.2%)脑膜炎奈瑟菌。在凉爽干燥季节观察到的细菌性脑膜炎增加主要归因于流感嗜血杆菌和肺炎链球菌。发现这些细菌菌株对通常使用的抗生素敏感。然而,近22%的流感嗜血杆菌菌株对氨苄西林或氯霉素耐药。观察到高死亡率(33%),尤其是肺炎链球菌感染导致的。化脓性细菌性脑膜炎在热带地区是一个极其重要的儿科问题。